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Chronic Heart Failure clinical trials

View clinical trials related to Chronic Heart Failure.

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NCT ID: NCT01993537 Completed - Clinical trials for Vitamin D Deficiency

The Role of Vitamin D in the Pathophysiology of Chronic Failure

Start date: January 2013
Phase: Phase 4
Study type: Interventional

Patients will undergo at baseline and regular intervals: - clinically indicated bloodwork/urine and echocardiogram testing - biomarker studies Upon enrolment in the study patients will be divided into 4 groups normal, mildly deficient and severely deficient. Normal and mild vitamin D levels will receive no treatment while severe Vitamin D deficiency will be randomized (50/50) to receive no treatment or vitamin D treatment. They will be seen in the heart failure clinic every 6 months. The patients will be followed for 26 months.

NCT ID: NCT01982292 Completed - Clinical trials for Chronic Heart Failure

Safety of Repeat Doses of IV Serelaxin in Subjects With Chronic Heart Failure

RELAX-REPEAT
Start date: May 2014
Phase: Phase 2
Study type: Interventional

The purpose of this study is to assess the safety of repeat doses of serelaxin in chronic heart failure. At the same time, markers of efficacy will also be collected as exploratory measures.

NCT ID: NCT01966458 Completed - Clinical trials for Chronic Heart Failure

A Clinical Trial to Evaluate the HeartWare™ Ventricular Assist System (ENDURANCE SUPPLEMENTAL TRIAL)

DT2
Start date: October 2013
Phase: N/A
Study type: Interventional

This is a prospective, randomized, controlled, unblinded, multi-center evaluation of safety and efficacy in patients implanted with a HeartWare® HVAD who receive improved blood pressure management. Subjects have chronic Stage D or NYHA Class IIIB/IV left ventricular failure who have received and failed optimal medical therapy, and who are ineligible for cardiac transplantation.

NCT ID: NCT01939236 Completed - Clinical trials for Chronic Heart Failure

Traditional Chinese Medicine for Treatment of Chronic Heart Failure

Start date: May 2010
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether traditional Chinese medicine as complementary treatment is safe and effective in the treatment of chronic heart failure.

NCT ID: NCT01919918 Completed - Clinical trials for Chronic Heart Failure

Muscle Afferent Feedback Effects in Patients With Heart Failure

Start date: September 2013
Phase: Phase 1
Study type: Interventional

The purpose of the study is to find out more about the mechanism by which neural feedback from the working muscle affects the development of central fatigue during exercise. Subjects with chronic heart failure (HF) and healthy subject counterparts will be tested to determine the mechanisms accounting for the premature fatigue characterizing HF patients during physical activity.

NCT ID: NCT01878630 Completed - Clinical trials for Chronic Heart Failure

Telemedical Interventional Management in Heart Failure II

TIM-HF2
Start date: August 8, 2013
Phase: Phase 3
Study type: Interventional

Superiority of additional Remote Patient Management (RPM) in patients with chronic heart failure (CHF) in comparison to usual care in terms of, e.g.: - days lost due to unplanned cardiovascular hospitalization or death - all-cause mortality - cardiovascular mortality - quality of life

NCT ID: NCT01831128 Completed - Clinical trials for Chronic Heart Failure

French Cohort Study of Chronic Heart Failure Patients With Central Sleep Apnoea Eligible for Adaptive Servo-Ventilation (PaceWave, AutoSet CS)

FACE
Start date: November 2009
Phase:
Study type: Observational

The purpose of FACE study is to provide in routine practice complementary long-term data on the mortality and morbidity of Chronic Heart Failure (CHF) patients with Central Sleep Apnea eligible for Adaptative Servo-Ventilation (ASV) treatment (PaceWave, AutoSet CS; ResMed).

NCT ID: NCT01813331 Completed - Clinical trials for Chronic Heart Failure

ALERT-HF: Adherence to Guidelines in the Treatment of Patients With Chronic Heart Failure

ALERT-HF
Start date: November 2012
Phase: N/A
Study type: Observational [Patient Registry]

ALERT-HF is an observational study aimed to evaluate the diagnostic criteria adopted and the adherence to the current therapeutic guidelines in a large series of patients affected with chronic heart failure. Secondary objective is to evaluate the prevalence of chronic heart failure among all the patients referring to the ambulatory cardiologists of the healthcare district.

NCT ID: NCT01804816 Completed - Clinical trials for Chronic Heart Failure

Acupuncture on Cardiac and Autonomic Function in Human Heart Failure

Start date: February 2013
Phase: N/A
Study type: Interventional

Acupuncture treatment may improve the cardiac function and the quality of life in heart failure patients. These effects may be related to the inhibition of sympathetic activity and/or increased vagal function. The suppression of inflammatory reaction with acupuncture treatment may also be associated with these outcomes. Specific aims include: 1. To evaluate the effect of acupuncture treatment on human cardiac sympathetic/vagal activity 2. To evaluate the effect of acupuncture treatment on cardiac function and functional capacity 3. To evaluate the general health score of the quality-of-life with acupuncture treatment 4. To explore the mechanism of acupuncture treatment on inflammation and nitrative stress in heart failure patients.

NCT ID: NCT01801722 Completed - Clinical trials for Chronic Obstructive Pulmonary Disease

Using NT-proBNP to Detect Chronic Heart Failure in Patients With Chronic Obstructive Pulmonary Disease

NT-proBNP
Start date: April 2008
Phase: N/A
Study type: Observational

The aim of the present study was to evaluate if the analysis of NT-proBNP might be used as an initial step for the diagnosis of chronic heart failure in patients with COPD in primary health care, and to select patients for a further examination by echocardiography.