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Ofatumumab as Primary Therapy of Chronic Graft Versus Host Disease

Chronic Graft Versus Host Disease Clinical Trial

Official title:
Ofatumumab in Combination With Glucocorticoids for Primary Therapy of Chronic Graft Versus Host Disease

Clinical Trial Summary

To study the safety and side effects of Ofatumumab in the treatment of chronic graft-versus-host disease (GvHD). This study will also evaluate effectiveness of Ofatumumab when added to standard steroid treatment for chronic graft-versus-host disease

Clinical Trial Description

This is a phase I-II trial to examine the safety and efficacy of prednisone and escalating dose of ofatumumab for the primary therapy of chronic GVHD. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01680965
Study type Interventional
Source H. Lee Moffitt Cancer Center and Research Institute
Contact
Status Completed
Phase Phase 1/Phase 2
Start date November 14, 2012
Completion date August 30, 2020
View Details
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