Efficacy of Linaclotide in Type II Diabetics With Chronic Constipation

Status Active, not recruiting

Clinical Trial Summary

Study includes 5 visits, when all basic clinical information, vital signs, symptoms, and side effects are going to be assessed at each appointment. Patients are going to be assigned by the computer, to receive an active or non-active drug for 14 days in a first phase. The order will be change during the second phase. The 2 weeks break without our medication will separate these phases. A very close observation regarding safety of our subjects will be implemented by study personnel and clinical investigators.

Clinical Trial Description

The symptoms of chronic constipation are defined as infrequent bowel movements, hard stool, straining during defecation, bloating, abdominal discomfort, and sensation of incomplete evacuation. Constipation has been reported as a common complication of diabetic neuropathy. A new medication, called linaclotide, was studied on many patients, and it is approved to be on a market for constipated patients. Unfortunately diabetics were not included in these previous studies; hence we designed the project which is going to address the possible benefit of this drug in diabetic population. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT03119584
Study type	Interventional
Source	Texas Tech University Health Sciences Center, El Paso
Contact
Status	Active, not recruiting
Phase	Phase 4
Start date	September 1, 2015
Completion date	January 30, 2025

View Details

See also
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