Clinical Trials Logo

Clinical Trial Summary

This study is aimed at studying the effectiveness and safety of surgical treatment of chronic anal fissure.


Clinical Trial Description

A chronic anal fissure is a rupture of the mucous membrane of the anal canal, lasting more than 2 months and resistant to non-surgical treatment. This condition is accompanied by a strong pain syndrome during and after defecation (defecation). This condition is most often found in young and able-bodied adults, so the issue of treatment is of particular relevance. The main cause of the development of a chronic anal fissure is a spasm of the internal sphincter. It should be eliminated first of all to ensure effective therapy.The investigators plan to treat a chronic anal fissure by performing a lateral subcutaneous sphincterotomy, without excision of the fissure. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05117697
Study type Interventional
Source State Scientific Centre of Coloproctology, Russian Federation
Contact
Status Recruiting
Phase N/A
Start date November 1, 2021
Completion date May 1, 2023

See also
  Status Clinical Trial Phase
Completed NCT03554421 - Percutaneous Tibial Nerve Stimulation - an Alternative Treatment Option for Chronic Therapy Resistant Anal Fissure N/A
Recruiting NCT05598164 - Botulinum Toxin Type A in the Treatment of Chronic Anal Fissure N/A
Terminated NCT02158013 - Treatment Of Chronic Anal Fissure N/A
Completed NCT01217515 - Diltiazem Hydrochloride Cream for Anal Fissure Phase 3
Completed NCT02527109 - The Effect of Intra-anal Nifedipine, Used As Add-on to Conservative Therapy, on Pain in Patients With Anal Fissure Phase 2/Phase 3
Recruiting NCT03920449 - Postero-lateral Internal Sphincterotomy vs Botulinum Toxin Injection in the Treatment of Chronic Anal Fissure N/A
Enrolling by invitation NCT04793347 - Effect of Shock Waves Therapy on Chronic Anal Fissure N/A
Completed NCT04166175 - High Dose Multiple Site Injection of Botox Versus Lateral Sphincterotomy in Chronic Analfissure N/A
Completed NCT02395809 - Transcutaneous Posterior Tibial Nerve Stimulation for Treatment of Chronic Anal Fissure N/A
Completed NCT01500889 - Conventional Lateral Internal Sphincterotomy, V-Y Anoplasty and Tailored Lateral Internal Sphincterotomy With V-YF in Treatment of Chronic Anal Fissure(CAF) N/A
Completed NCT01132391 - Perianal Versus Endoanal Application of Glyceryl Trinitrate 0.4% Ointment for Chronic Anal Fissure Phase 3
Completed NCT03872765 - Outcomes of the Use of CO2 (Carbon Dioxide) Laser in the Treatment of Chronic Anal Fissure N/A
Completed NCT00972907 - An Open Label Study to Examine the Effect of Coated Nifedipine Suppository on Anal Fissure Pain and Healing in Human Subjects Phase 1/Phase 2