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Clinical Trial Summary

This study aims to validate a non-invasive method of chromosomal screening (NICS), based on the Multiple Annealing and Looping Based Amplification Cycles- Next-generation Sequencing (MALBAC-NGS) technology, in order to determine the chromosomal endowment of a blastocyst from the DNA of the embryonic culture medium.

The chromosomal status of the embryo from an embryo biopsy of trophoectoderm will be established (usual clinical practice), the chromosomal endowment from the DNA of the embryonic culture medium will be determined, and the results using the NICS and the conventional invasive method (Preimplantation Genetic Testing for Aneuploidy [PGT-A]) will be compared.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03879265
Study type Observational
Source Instituto Bernabeu
Contact
Status Completed
Phase
Start date February 1, 2019
Completion date January 20, 2020

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