Chromosome Abnormality Clinical Trial
Official title:
Validation of a Noninvasive Chromosome Screening (NICS) Method Using the Culture Medium
This study aims to validate a non-invasive method of chromosomal screening (NICS), based on
the Multiple Annealing and Looping Based Amplification Cycles- Next-generation Sequencing
(MALBAC-NGS) technology, in order to determine the chromosomal endowment of a blastocyst from
the DNA of the embryonic culture medium.
The chromosomal status of the embryo from an embryo biopsy of trophoectoderm will be
established (usual clinical practice), the chromosomal endowment from the DNA of the
embryonic culture medium will be determined, and the results using the NICS and the
conventional invasive method (Preimplantation Genetic Testing for Aneuploidy [PGT-A]) will be
compared.
n/a
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