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The Short-term Effects of Simvastatin on the Vision of Males Affected by Choroideremia

Choroideremia Clinical Trial

Official title:
A Repeated Measures Study of Simvastatin on Choroideremia: Simvastatin Intervention and Reversal in Choroideremia Patients and Age-matched Controls.

Clinical Trial Summary

Primary objective: To examine the short-term effects of of simvastatin on the vision on males with choroideremia, evaluated by full-field scotopic threshold testing. The investigators hypothesize that they will see a reversible decrease in the dark-adapted vision in participants taking simvastatin.

Clinical Trial Description

n/a

Study Design

Allocation: Non-Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Crossover Assignment, Masking: Open Label, Primary Purpose: Supportive Care

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT01654562
Study type Interventional
Source University of Alberta
Contact
Status Terminated
Phase Phase 1/Phase 2
Start date December 2012
Completion date July 2013
View Details
See also
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