A Study to Assess Choroideremia (CHM) Health Outcomes

Status Completed

Clinical Trial Summary

The primary objectives of this study are to describe disease progression and severity by age in participants with CHM, to assess health-related quality-of-life, resource utilization and work productivity, and to assess quality-of-life, work productivity, and impact on daily activities in caregivers of participants with CHM at different stages of disease progression.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Choroideremia

Clinical Trial Details

NCT number	NCT04750785
Study type	Observational
Source	Biogen
Contact
Status	Completed
Phase
Start date	December 15, 2020
Completion date	September 27, 2021

View Details

See also
Status	Clinical Trial	Phase
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Withdrawn	`NCT05045703` - The Dark-Adapted Retinal Function Response in Choroideremia (DARC) Study	N/A
Recruiting	`NCT01866371` - High Resolution Retinal Imaging
Completed	`NCT01603576` - Pilot Study of a Suprachoroidal Retinal Prosthesis	N/A
Enrolling by invitation	`NCT03584165` - Long-term Safety and Efficacy Follow-up of BIIB111 for the Treatment of Choroideremia and BIIB112 for the Treatment of X-Linked Retinitis Pigmentosa	Phase 3
Completed	`NCT03359551` - Natural History of the Progression of Choroideremia Study
Recruiting	`NCT02435940` - Inherited Retinal Degenerative Disease Registry
Active, not recruiting	`NCT04483440` - Dose Escalation Study of Intravitreal 4D-110 in Patients With Choroideremia	Phase 1
Completed	`NCT02670980` - Compensation for Blindness With the Intelligent Retinal Implant System (IRIS V2) in Patients With Retinal Dystrophy	N/A
Completed	`NCT02671539` - THOR - Tübingen Choroideremia Gene Therapy Trial	Phase 2
Completed	`NCT02341807` - Safety and Dose-escalation Study of AAV2-hCHM in Participants With CHM (Choroideremia) Gene Mutations	Phase 1/Phase 2
Completed	`NCT03406416` - Study of a Suprachoroidal Retinal Prosthesis	N/A
Enrolling by invitation	`NCT05158049` - Longitudinal Study of a Bionic Eye
Terminated	`NCT02994368` - "Natural History" Study of Choroideremia
Terminated	`NCT01654562` - The Short-term Effects of Simvastatin on the Vision of Males Affected by Choroideremia	Phase 1/Phase 2
Active, not recruiting	`NCT00427180` - IRIS PILOT - Extended Pilot Study With a Retinal Implant System	N/A