Clinical Trials Logo

Cholecystectomy, Laparoscopic clinical trials

View clinical trials related to Cholecystectomy, Laparoscopic.

Filter by:

NCT ID: NCT06193837 Not yet recruiting - Clinical trials for Cholecystectomy, Laparoscopic

Prophylactic Antibiotic in Non-complicated Low Risk Lap Cholecystectomy (LC)

Start date: January 1, 2024
Phase:
Study type: Observational

To Compare between outcomes of Antibiotic Prophylaxis and No antibiotic prophylaxis in non-complicated low risk laparoscopic cholecystectomy

NCT ID: NCT06074679 Recruiting - Clinical trials for Cholecystectomy, Laparoscopic

Clinical Study of Single Incision Laparoscopic Cholecystectomy in the Treatment of Patients With Acute Cholecystitis

Start date: September 30, 2023
Phase: N/A
Study type: Interventional

Gallstone is a common disease in China.At present, the prevalence of gallstones in China is 15 %, and about 210 million people are sick. Acute cholecystitis is acute gallbladder inflammation, is one of the main complications of cholelithiasis or gallstones. The removal of gallbladder and gallstones in patients with acute cholecystitis in the presence of biliary pain will prevent the recurrence of gallbladder and reduce the risk of cholecystitis progression. If gallbladder perforation is not treated in time, the mortality rate is 30 %. Acute acalculous cholecystitis without treatment will be life-threatening, with a mortality rate of up to 50 %. At present, the vast majority of patients with acute cholecystitis are treated with 4-hole traditional laparoscopic cholecystectomy and open cholecystectomy. Their postoperative quality of life, pain and scar-related complications, remain major factors for patients.In recent years, with the renewal of the concept of minimally invasive surgery and the continuous advancement of instruments and technology, single-incision laparoscopic cholecystectomy has also maximized the quality of life after surgery and reduced postoperative pain and scar-related complications. At present, there are few reports on randomized controlled clinical trials of SILC in patients with acute cholecystitis, and there is a lack of large sample size studies.Due to the difficulty of SILC operation, the longer learning curve, the different equipment conditions and technical characteristics of each center, and the lack of standardized training, there is no effective consensus on the application indications and operation procedures of SILC in acute cholecystitis surgery. Based on the current status, the purpose of this study was to investigate the effect of SILC on postoperative quality of life, postoperative pain, scar assessment and postoperative complications in patients with acute cholecystitis, so as to propose a standardized single incision laparoscopic operation procedure in the treatment of acute cholecystitis.

NCT ID: NCT05728463 Recruiting - Clinical trials for Cholecystectomy, Laparoscopic

Single Incision Laparoscopic Cholecystectomy Compared With Conventional Laparoscopic Cholecystectomy, a Randomized Controlled Clinical Study

Start date: February 6, 2023
Phase: N/A
Study type: Interventional

Laparoscopic cholecystectomy has been accepted and is nowadays considered as the gold standard treatment of gallstones disease. Conventional laparoscopic cholecystectomy (CLC) was defined as three or four port surgery carried out with either French or American position. It reduced post-operative pain and shorten post-operative length of stay compared with open cholecystectomy in a great extent. Single-incision laparoscopic cholecystectomy (SILC) as a revolutionized surgery, the main reason for its widespread use being the following: less post-operative pain, faster recovery, better cosmetics and quicker return to full activities, all resulting in the improvement of post-operative quality of life. SILC uses the umbilicus as a natural orifice allowing easy access to peritoneal cavity, easy conversion to standard laparoscopy and its easy closure, has been widely introduced into the clinical practice for benign gallbladder diseases. SILC can easily hide the surgical scar inside the umbilicus, thus has better cosmetic effect. But the real clinical benefits for patients still remain a matter of debate. In the last 5 years, many studies on SILC have been published, trying to answer the question whether such a new approach is worthwhile or not and whether is safe and cost-effective.Based on the above controversy, we conduct a RCT comparing clinical and peri-operative outcomes, such as quality of life (QOL), of SILC and CLC with the intent to assess the actual indications of the single-incision approach.

NCT ID: NCT05728073 Completed - Clinical trials for Cholangiopancreatography, Endoscopic Retrograde

Does Subtotal Cholecystectomy Rate for Acute Cholecystitis Change With a Previous ERCP?

Start date: December 10, 2022
Phase:
Study type: Observational

Study is designed to investigate whether the history of ERCP is associated with subtotal cholecystectomy rates in patients underwent laparoscopic cholecystectomy operations with the diagnosis of acute cholecystitis.

NCT ID: NCT05532436 Completed - Clinical trials for Cholecystectomy, Laparoscopic

The Effect of Breath Exercise on Patients' Post-Operative Anxiety Level, Sleep and Recovery Quality

Start date: December 1, 2020
Phase: N/A
Study type: Interventional

This study was conducted to determine the effect of breath exercise on post-operative anxiety level, sleep and recovery quality after laparoscopic cholecystectomy surger. This was a randomized controlled experimental study. The sample comprised 115 patients who underwent laparoscopic cholecystectomy (control:57; experimental:58). One day before the operation, the participants in the experimental group were given breathing exercise training, and they were applied 5 times a day for 10 repetitions until the 30th day after the operation.

NCT ID: NCT05214157 Completed - Clinical trials for Cholecystectomy, Laparoscopic

Optimizing Pain Management Following Laparoscopic Cholecystectomy RCT

Pain
Start date: March 20, 2020
Phase: N/A
Study type: Interventional

evaluating the two final steps we added to optimize post laparoscopic cholecystectomy pain management.

NCT ID: NCT04745273 Completed - Clinical trials for Cholecystectomy, Laparoscopic

Interaction Between Tramadol and Ondansetron

Start date: September 2, 2020
Phase: Phase 4
Study type: Interventional

In the postoperative period; pain, nausea, and vomiting are undesirable side effects that reduce the patient's comfort and may lead to various complications. Ondansetron is frequently used as an antiemetic and tramadol hydrochloride is used for postoperative analgesia in laparoscopic cholecystectomy. However, some studies have reported that there is a drug interaction between these two drugs and they reduce each other's effects, thus requiring more analgesics in the postoperative period. The aim of this study is; To evaluate whether ondansetron reduces the analgesic efficacy of tramadol hydrochloride in laparoscopic cholecystectomies.

NCT ID: NCT04254237 Completed - Incisional Hernia Clinical Trials

Trocar Site Hernia After Laparoscopic Cholecystectomy, Supra Versus Infraumbilical Incision for Umbilical Trocar Entry

HOT
Start date: February 6, 2020
Phase: N/A
Study type: Interventional

Trocar site hernia is a specific complication of laparoscopic surgery. The increasingly frequent use of the laparoscopic approach has resulted in an increase in the number of hernias, mainly at the umbilical area. The appearance of a trocar site hernia can cause complications in the short and long term to the patient who may end up needing a reoperation. In this study we want to compare the supraumbilical versus the infraumbilical location of the laparoscopy entry trocar, in terms of incisional hernia incidence.

NCT ID: NCT03794271 Completed - Anesthesia, General Clinical Trials

Effect of Pupilometer Guided Analgesia on Postoperative Pain

PUPIL_pain
Start date: January 3, 2019
Phase: N/A
Study type: Interventional

In this study, the investigators measure a pupil size every 5 minutes during the operation in patients undergoing laparoscopic cholecystectomy under general anesthesia. The investigators would compare the postoperative pain intensity between the group adjusted the anesthetic drug concentration based on the changes of the pupil (Pupil group) and the group based on the changes of a surgical pleth index (SPI group).

NCT ID: NCT03586791 Completed - Anesthesia, General Clinical Trials

Comparison of Pupillometry-guided Anesthesia With Surgical Pleth Index Guided Anesthesia

PUPIL
Start date: July 11, 2018
Phase: N/A
Study type: Interventional

In this study, the investigators measure a pupil size every 5 minutes during the operation in patients undergoing laparoscopic cholecystectomy under general anesthesia. The investigators would compare the intraoperative opioid consumption and postoperative pain between the group adjusted the anesthetic drug concentration based on the changes of the pupil (Pupil group) and the group based on the changes of a surgical pleth index (SPI group).