Biliary Atresia Clinical Trial
Official title:
Establishment and Validation of a Standardized Definition for Biliary Atresia Associated Cholangitis After Hepatic Portoenterostomy
Cholangitis is the most common postoperative complication of biliary atresia, with a reported incidence of 40-90%, which seriously affects the surgical effect, survival rate and the quality of life and prognosis of patients. Without of direct evidence, the diagnosis of cholangitis sometimes is difficult to make, thus most of them are diagnosed based on the symptoms of children. According to literature reports, different centers and regions have different diagnostic criteria for postoperative cholangitis after hepatic portoenterostomy, which has a great influence on the accuracy of the incidence rate and appropriate treatment of cholangitis, and also brings differences in the analysis of the causes and prognostic factors of cholangitis. Based on the above reasons, we used the Delphi method,in which worldwidely 48 experts participated in, to establish the diagnostic scoring system for postoperative cholangitis after biliary atresia. Now we aimed to verify the specificity and sensitivity of the new scoring system through clinical cases, in order to unify and standardize the diagnostic criteria and provide help for the diagnosis and treatment of cholangitis after biliary atresia.
n/a
Status | Clinical Trial | Phase | |
---|---|---|---|
Enrolling by invitation |
NCT03667534 -
Dry Blood Spot Screening Test for Neonatal Cholestasis Patients
|
||
Completed |
NCT02652533 -
Ultrasound Shear Wave Elastography Evaluation of Suspected and Known Biliary Atresia
|
||
Completed |
NCT01443572 -
The Comparison of Desflurane and Sevoflurane on Postoperative Recovery and Hepatic Function of Biliary Atresia Patients During Kasai Operation
|
N/A | |
Recruiting |
NCT04373941 -
Part II: Granulocyte-Colony Stimulating Factor Adjunct Therapy for Biliary Atresia
|
Phase 2 | |
Completed |
NCT01854827 -
Safety Study of Intravenous Immunoglobulin (IVIG) Post-Portoenterostomy in Infants With Biliary Atresia
|
Phase 1/Phase 2 | |
Completed |
NCT00007033 -
Study of Magnesium Sulfate in Children With Reduced Bone Density Secondary to Chronic Cholestatic Liver Disease
|
N/A | |
Recruiting |
NCT05848310 -
Preoperative Serum FGF19 in the Prognosis of Biliary Atresia
|
||
Recruiting |
NCT05072626 -
High Medium-chain Triglyceride Nutritional Support in Infants With Biliary Atresia
|
||
Completed |
NCT02292862 -
Maternal Microchimerism in Lymph Nodes of Infants With Biliary Atresia at Time of Kasai's Operation
|
N/A | |
Completed |
NCT00294684 -
A Randomized, Double-Blinded, Placebo-Controlled Trial of Corticosteroid Therapy Following Portoenterostomy
|
N/A | |
Active, not recruiting |
NCT02922751 -
FibroScan™ in Pediatric Cholestatic Liver Disease (FORCE)
|
||
Recruiting |
NCT06184971 -
Biliary Atresia Research Network Northeast
|
||
Recruiting |
NCT04260503 -
Gut Microbiome in Biliary Atresia
|
||
Not yet recruiting |
NCT06260566 -
Tolerability of Enteral NAC in Infants
|
Phase 1 | |
Completed |
NCT01322386 -
Gastrointestinal Microbiota in Primary Sclerosing Cholangitis and Biliary Atresia With Vancomycin
|
Phase 1 | |
Recruiting |
NCT05909033 -
Early Predictors for the Short Term Native Liver Survival in Patients With Biliary Atresia After Kasai Procedure
|
||
Completed |
NCT03499249 -
N-Acetylcysteine in Biliary Atresia After Kasai Portoenterostomy
|
Phase 2 | |
Recruiting |
NCT00345553 -
Biliary Atresia Study in Infants and Children
|
||
Recruiting |
NCT05521152 -
Norepinephrine for Prevention of Intraoperative Hypotension in Infants Undergoing Kasai Portoenterostomy
|
Phase 3 | |
Not yet recruiting |
NCT05783518 -
Effect of Desflurane on Pediatric Acute Respiratory Distress Syndrome After Living Donor Liver Transplant Recipients
|
Phase 4 |