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Cholangitis clinical trials

View clinical trials related to Cholangitis.

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NCT ID: NCT06327126 Recruiting - Clinical trials for Choledocholithiasis With Acute Cholangitis

Efficacy and Safety of Single-session Endoscopic Stone Extraction

Start date: January 1, 2024
Phase:
Study type: Observational

This is a retrospective study, including approximately 600 patients with acute cholangitis accompanied with choledocholithiasis, who treated with single-session or two-session endoscopic stone extraction at Beijing friendship hospital. The investigators assessed the outcomes of single-stage and two-stage endoscopic stone extraction.

NCT ID: NCT06309589 Completed - Clinical trials for Primary Biliary Cholangitis

The Effectiveness of Combining Ursodeoxycholic Acid With Vitamin D in Treating Patients With Primary Biliary Cholangitis

Start date: May 1, 2021
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to compare in the effectiveness of combining ursodeoxycholic acid and vitamin D in treating patients with primary biliary cholangitis.

NCT ID: NCT06297993 Not yet recruiting - PSC Clinical Trials

Adult Patients With Primary Sclerosing Cholangitis

WIND-PSC
Start date: March 2024
Phase:
Study type: Observational

Develop an appropriate real-world data comparator cohort to support the design, execution, and serve as an external control for interventional clinical trials in PSC.

NCT ID: NCT06286709 Not yet recruiting - Clinical trials for Inflammatory Bowel Diseases

FAecal Microbiota Transplantation in primaRy sclerosinG chOlangitis

FARGO
Start date: February 29, 2024
Phase: Phase 2
Study type: Interventional

FARGO is a randomised, phase IIa, multi-centre, placebo-controlled trial to compare Faecal Microbiota Transplant (FMT) with placebo in patients with primary sclerosing cholangitis (PSC) and concomitant inflammatory bowel disease.

NCT ID: NCT06252610 Not yet recruiting - PSC Clinical Trials

PET/MRI of Primary Sclerosing Cholangitis

Start date: April 10, 2024
Phase:
Study type: Observational

This study aims to use positron emission tomography (PET)/magnetic resonance imaging (MRI) to diagnose and quantify PSC-related biliary tract fibrosis and to improve upon the currently available non-invasive diagnostic capabilities by investigating the ability of combined PET/MRI to detect and quantify fibrosis using a novel collagen-binding radiotracer. Specifically, the investigators will be comparing [68Ga]CBP8- and [18F]-FAPI-74 PET/MRI to a liver transient elastography scan in the diagnosis of biliary tree fibrosis.

NCT ID: NCT06247735 Recruiting - Clinical trials for Primary Biliary Cholangitis

Study to Evaluate the Efficacy and Safety of K-808 (Pemafibrate) in Participants With Primary Biliary Cholangitis (PBC) With Inadequate Response to Ursodeoxycholic Acid (UDCA) and/or Obeticholic Acid (OCA) Treatment.

Start date: January 26, 2024
Phase: Phase 2
Study type: Interventional

Study to investigate the efficacy and safety of two doses of K-808 (pemafribate) in subjects with PBC.

NCT ID: NCT06197984 Recruiting - Choledocholithiasis Clinical Trials

Antimicrobial Resistance in Acute Cholangitis

ARISE
Start date: January 8, 2024
Phase:
Study type: Observational [Patient Registry]

This study prospectively explores antimicrobial resistance in patients with acute cholangitis undergoing ERCP procedures. By analyzing patient profiles, microbial cultures, and treatment outcomes, the current study seeks to identify specific patterns of resistance, assess the effectiveness of current antimicrobial therapies, and explore potential strategies to optimize treatment regimens.

NCT ID: NCT06197308 Not yet recruiting - Clinical trials for Primary Sclerosing Cholangitis

Evaluation of an Oral Microbiota-based Therapeutic as a Treatment Option for PSC

Start date: March 1, 2024
Phase: Early Phase 1
Study type: Interventional

This pilot clinical trial will evaluate the initial safety and feasibility of microbiota transplant therapy (MTT) inpatients with primary sclerosing cholangitis (PSC). This trial will inform development of future trials in treatment of PSC.

NCT ID: NCT06174402 Recruiting - Clinical trials for Primary Biliary Cholangitis

Fenofibrate in Combination With Ursodeoxycholic Acid in Primary Biliary Cholangitis

Start date: August 21, 2023
Phase: Phase 2/Phase 3
Study type: Interventional

The main objectives of the study were to assess the effects of fenofibrate on serum alkaline phosphatase, as a composite endpoint and on safety in participants with primary biliary cholangitis (PBC)

NCT ID: NCT06141395 Recruiting - Pneumonia Clinical Trials

NGS-Based Assay of Blood Samples of Sepsis Patients for Rapid Bacterial Identification

BIOARTE
Start date: November 16, 2023
Phase:
Study type: Observational

Rapid detection of microorganisms is a promising approach towards early administration of appropriate antibiotics for sepsis. This study aims to investigate the potential of a new NGS platform for the rapid diagnosis of circulating bacteria in blood.