Children Clinical Trial
Official title:
Application of HFNC for the Prevention of Hypoxemia During Perioperative Anesthetic-induced Intubation in Children: A Randomized Controlled Clinical Trial
NCT number | NCT06425406 |
Other study ID # | HFNC |
Secondary ID | |
Status | Recruiting |
Phase | N/A |
First received | |
Last updated | |
Start date | December 4, 2023 |
Est. completion date | May 1, 2025 |
Compared with adults, children have higher metabolic needs, and the airway is more likely to collapse. Before tracheal intubation after anesthesia induction, the patient 's spontaneous breathing completely disappears. At this critical stage, the residual oxygen of the lung is consumed, resulting in hypoxemia and atelectasis. Therefore, it is necessary to explore the best oxygenation strategy during intubation. In addition, ultrasound has become a common equipment in the operating room. It has the advantages of portability, repeatability, and no radiation, and can provide strong support for the diagnosis of gastric distension.
Status | Recruiting |
Enrollment | 48 |
Est. completion date | May 1, 2025 |
Est. primary completion date | May 1, 2025 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 2 Years to 10 Years |
Eligibility | Inclusion Criteria: - Age 2-10 years old; - American Society of Anesthesiologists (ASA) Level I or II; - Children with healthy lungs and hearts; - Clear headed and able to cooperate with anesthesiologists for treatment. Exclusion Criteria: - Contraindications for HFNC: (1) Complete obstruction of the upper respiratory tract; (2) Skull base fracture or nasal bone fracture; (3) Patients who refuse to use HFNC; - The American Society of Anesthesiologists (ASA) rating is greater than Level II; - Children with upper respiratory tract infections within 2 weeks; - Pulmonary dysfunction, congenital heart disease in children; |
Country | Name | City | State |
---|---|---|---|
China | Department of Anaesthesiology and Perioperative Medicine, People's Hospital of Zhengzhou University, Henan Provincial People's Hospital | Zhengzhou | Henan |
Lead Sponsor | Collaborator |
---|---|
Henan Provincial People's Hospital |
China,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Apnoea time | Investigators will record the time of oxygen saturation drop to 95 % during intubation. | 2-10min |
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