Children Clinical Trial
— PrediDengueOfficial title:
New Tools for Predicting Capillary Leak Shock During Dengue Fever
NCT number | NCT04422782 |
Other study ID # | PrediDengue |
Secondary ID | |
Status | Recruiting |
Phase | N/A |
First received | |
Last updated | |
Start date | May 14, 2020 |
Est. completion date | May 14, 2023 |
Evaluate the prognostic value of different methods (Osmometry / clinical-biological score) compared to the occurrence of capillary leak shock during dengue fever.
Status | Recruiting |
Enrollment | 342 |
Est. completion date | May 14, 2023 |
Est. primary completion date | May 14, 2022 |
Accepts healthy volunteers | No |
Gender | All |
Age group | 5 Years and older |
Eligibility | Inclusion Criteria: - Age> = 5 years - Patient / parent consent - Exclude other pathology with capillary circulation problem (septic shock, anaphylaxis) All suspected dengue fever requiring hospitalization will be included, final inclusion being after biological confirmation (AgNS1, RT-PCR, serology). Exclusion Criteria: - Age <5 years - Refusal to participate - Unsigned consent - Coinfection by another agent - Patient under guardianship or curatorship. |
Country | Name | City | State |
---|---|---|---|
France | General Hospital of Cayenne | Cayenne | French Guiana |
Lead Sponsor | Collaborator |
---|---|
Centre Hospitalier de Cayenne | European Regional Development Fund |
France,
Djossou F, Vesin G, Elenga N, Demar M, Epelboin L, Walter G, Abboud P, Le-Guen T, Rousset D, Moreau B, Mahamat A, Malvy D, Nacher M. A predictive score for hypotension in patients with confirmed dengue fever in Cayenne Hospital, French Guiana. Trans R Soc Trop Med Hyg. 2016 Dec 1;110(12):705-713. doi: 10.1093/trstmh/trx004. — View Citation
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Occurrence of a shock | The primary outcome measure will be the occurrence of a shock defined by systolic blood pressure <90 mm Hg in adults and <80 mm Hg in children. | 2 years | |
Secondary | Predictive value of plasma hypo-osmolarity | Evaluate the predictive value of plasma hypo-osmolarity in the occurrence of shock during dengue | 2 years | |
Secondary | Validation of the clinical-biological prognostic score | Prospectively validate the clinical-biological prognostic score (2013 shock score) and, if possible, improve it | 2 years | |
Secondary | Relationship between the measurements obtained by osmolarity and capillary leakage | Study the relationship between the measurements obtained by osmolarity and capillary leakage measured by pleural effusion | 2 years | |
Secondary | Evaluation of the sensitivity / specificity and predictive values of osmolarity and capillary leakage | Evaluation of the sensitivity / specificity and predictive values of these measures in relation to the ultrasound objectification of a pleural effusion | 2 years | |
Secondary | How long before the shock these measures (osmolarity, score) allow to predict an unfavorable evolution | Specify how long before the shock these measures (osmolarity, score) allow to predict an unfavorable evolution | 2 years | |
Secondary | Association between the factor "Presence of sickle cell disease" and "occurrence of severe dengue" | Study the association between the factor "Presence of sickle cell disease" and "occurrence of severe dengue" | 2 years |
Status | Clinical Trial | Phase | |
---|---|---|---|
Completed |
NCT03563196 -
Diagnosis Of Pulmonary Complications After Cardiac Surgery In Children
|
||
Completed |
NCT02553486 -
Internationally Adopted Children Quality of Life
|
N/A | |
Completed |
NCT02903134 -
Early Risk of Asthma in Children Exposed to In-utero Maternal Obesity
|
||
Completed |
NCT02918890 -
Intensive Unimanual (CIMT) and Bimanual Training (HABIT) in Children With Hemiplegia
|
N/A | |
Active, not recruiting |
NCT01874847 -
PLAY GAME: Post-concussion Syndrome in Youth - Assessing the GABAergic Effects of Melatonin
|
Phase 2/Phase 3 | |
Enrolling by invitation |
NCT01971827 -
Effectiveness of a Physical Activity Intervention to Prevent Obesity and Improve Academic Performance
|
N/A | |
Enrolling by invitation |
NCT01971840 -
Effectiveness of a Physical Activity Intervention on Preventing Obesity During the Adiposity Rebound Period.
|
N/A | |
Completed |
NCT01738308 -
The Effects of Healing Touch on Post Operative Pediatric Patients
|
N/A | |
Completed |
NCT01943760 -
Tamadol Wound Infiltration in Children Under Inguinal Hernioplasty
|
Phase 4 | |
Completed |
NCT01864811 -
Effect of Baby-CIMT in Infants Younger Than 12 Months
|
N/A | |
Completed |
NCT01693926 -
Effect of Physical Activity an Stress in Children
|
N/A | |
Completed |
NCT01323010 -
Efficacy and Safety of Increasing Doses of Inhaled Albuterol in Children With Acute Wheezing Episodes
|
N/A | |
Completed |
NCT01277224 -
Effectiveness of a Physical Activity Intervention on the Obesity of Schoolchildren
|
N/A | |
Active, not recruiting |
NCT00989547 -
Cord Blood Infusion for Type 1 Diabetes Mellitus (T1DM)
|
Phase 1 | |
Completed |
NCT04051723 -
Pre-emptive Scalp Infiltration With Dexamethasone Plus Ropivacaine for Post-Craniotomy Pain in Children
|
Phase 4 | |
Completed |
NCT03236363 -
Effectiveness of MOVI Interventions on Adiposity, Cognition and Motor Competence: MOVI-da10!
|
N/A | |
Completed |
NCT03236337 -
Effectiveness of MOVI Interventions on Adiposity, Cognition and Subclinical Atherosclerosis: MOVI-daFit!
|
N/A | |
Not yet recruiting |
NCT03427697 -
Effect of VR and Accommdation Relax on Controlling Myopia in Children
|
N/A | |
Completed |
NCT05603507 -
Inspiratory Muscle Training in Children With Chest Burn
|
N/A | |
Not yet recruiting |
NCT06267339 -
Effects of Transcranial Random Noise Stimulation on Motor Learning in Typically Developing Adolescents
|
Early Phase 1 |