Brain Lesion and Visuospatial Impairment in CP Child

Children With Cerebral Palsy Clinical Trial

— EVSP-ANAT-CP  

Official title:

Visuo-spatial Profile in Children With Cerebral Palsy Born at Term or Not and Anatomical Correlation

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT06131320
• Other study ID #: 69HCL23_1053
• Status: Recruiting
• Start date: September 1, 2022
• Est. completion date: April 2, 2024

Study information

• Verified date: November 2023
• Source: Hospices Civils de Lyon
• Contact: Sibylle Gonzalez-Monge
• Phone: 33472129477
• Email: sibylle.gonzalez-monge[@]chu-lyon.fr
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Children with cerebral palsy (CP) show varying degrees of motor impairment and movement disorders whose perceptive-visual contribution has yet to be established. The literature reports that children with CP have more frequent neuro-visual disorders. The link between the location and size of the brain lesion and neurovisual symptomatology has yet to be explored.

In this retrospective clinical data study, we will investigate in children with PC whether there is an anatomo-clinical correlation between visuo-spatial disorders is the brain injury of interest to the dorsal visual pathway. We will explore the volume of grey and white matter parietal involvement.

To test visuo-spatial disorders, we will use the PVSE (Visuo-Spatial Elementary Perception) test which does not require motor skills or language and is therefore suitable for children with a PC. This test will make it possible to better identify the deficit or deficits in order to adapt an early remediation. It could serve as a reference for comparing several pathologies/etiologies.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 150
• Est. completion date: April 2, 2024
• Est. primary completion date: December 31, 2023
• Gender: All
• Age group: 4 Years to 18 Years

Eligibility

Inclusion Criteria:

• Male or female aged 4 to 18 yo

• With a CP diagnosis

• With PVSE test completion during his/her regular follow-up

• With a cerebral MRI scan during his/her regular follow-up

Exclusion Criteria:

• With an incomplete PVSE test or whose interpretation was deemed unreliable by the rater

Related Conditions & MeSH terms

• Cerebral Palsy
• Children With Cerebral Palsy

Intervention

Diagnostic Test:
• PVSE Test
Completion of the PVSE test

Other:
• Cerebral MRI
Cerebral MRI scan

Locations

Country	Name	City	State
France	Pediatric rehabilitation unit of the Hospices Civils de Lyon	Bron

Sponsors (1)

Lead Sponsor	Collaborator
Hospices Civils de Lyon

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	PVSE test results: total score and 8 sub-scores (length perception, size perception, angle comparison, midline localization, position perception, position selection, occipital score and parietal score.)	Using normative values of PVSE test, we assess pathological measure inferior outlier limits and subnormal measure below the lower quartile limit	At the inclusion