The Impact of Synergies of Indoor Air Pollutants on Childhood Health &

Status Not yet recruiting

Clinical Trial Summary

To quantify health effects of synergizing chemical and biological pollutants in a targeted population setting, i.e., school-aged children. Indoor air pollutants will be monitored within the classrooms with high end sensors. Exposure data from additional sources (outdoor, home, transports) will be obtained. Health outcomes will be assessed prospectively using validated medical procedures and real-time tracking with mobile health (mHealth) equipment and a gamified computer app.

Clinical Trial Description

Communication with individual schools and families representing diverse cultural and socioeconomic backgrounds, will be conducted and formal participation consents obtained. The target population will include healthy children and be enriched for children with respiratory allergies and asthma. Provision of instructions, training for participation and baseline assessments of respiratory, immune, and mental health using questionnaires and relevant physiological measurements (e.g spirometry, FeNO), will be performed. Sensors will be positioned and cross-checked for functionality.Health data from the cohort will be monitored by a specifically designed gamified application, as well as by state-of-the-art wearable tracking technology. The app will capture input from the participants at large, while the trackers will accurately, continuously, and remotely, identify personalized patterns of all day activity status, heart rate, oxygen saturation, temperature, blood pressure, sleep, respiratory rate, and mechano-acoustic breathing sounds signatures. Sentinel data will be processed in Work Package 6 and integrated in the SynAir-G autonomous sensing platform. Children will be prospectively followed-up for a school year. Investigators will regularly visit schools to keep sensors running and collect materials. Real-time tracking will be coupled with regular communication and face-to-face visits for health outcome assessments. Devices will be positioned in selected locations. The cohort will also provide the setting for establishing indoor and outdoor interactions, dose-responses in real life, and health outcome data for integration and synergy analyses. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT05105386
Study type	Observational [Patient Registry]
Source	National and Kapodistrian University of Athens
Contact	PARASKEVI XEPAPADAKI, Assoc. Prof.
Phone	2132009160
Email	vickyxepapadaki@gmail.com
Status	Not yet recruiting
Phase
Start date	September 2023
Completion date	September 2027

View Details

See also
Status	Clinical Trial	Phase
Active, not recruiting	`NCT05541653` - The IGNITE Study on Concentrated Investment in Black Neighborhoods	N/A
Completed	`NCT04028791` - Sickle Cell Trait and Exercise, Effect of Hot Environment	N/A
Completed	`NCT05507944` - FeNO Hairdressers Pilot
Completed	`NCT04146025` - Nurtured in Nature	N/A
Recruiting	`NCT05179993` - Detection of Microplastics in Human Granulosa Cells and in the Follicular Fluid of Women Undergoing ICSI Treatment
Completed	`NCT03444922` - Effects of BPA on Insulin and Glucose Responses	N/A
Recruiting	`NCT03319927` - Reducing Pesticide Exposures in Child Care Centers	N/A
Recruiting	`NCT05500690` - Understanding Effects of Folic Acid on the Methylosome and Transcriptome of Women With Spina Bifida Affected Pregnancies	N/A
Recruiting	`NCT05394363` - Generation Victoria Cohort 2020s: A Statewide Longitudinal Cohort Study of Victorian Children and Their Parents
Completed	`NCT00021658` - Effects of Pesticide Exposure on Neurodevelopment/Growth/Respiratory Health	N/A
Not yet recruiting	`NCT05315388` - Effects of "Vitamin N" Nature Immersion Therapy on Stress Levels in Health Care Workers in the City of Bogotá	N/A
Recruiting	`NCT06107933` - Developmental Impacts of Microplastics Exposure in Early Life
Completed	`NCT03631667` - Ultralow Dose PAH Binary Mixture Study	Early Phase 1
Completed	`NCT02540408` - Detection and Characterization of COPD in Dairy Farmers	N/A
Completed	`NCT03440307` - Intervention to Reduce Bisphenol A Exposure in Women	N/A
Completed	`NCT05160948` - Change in Knowledge After Receiving Personal Air Pollution Results
Recruiting	`NCT05865782` - Reconstructing Schoolyards With Greenery to Increase Schoolchildren's Physical Activity and Mitigate Climate Changes	N/A
Completed	`NCT02707172` - Removal of Dermal Exposure to Phthalate Ester by Hand Washing	N/A
Active, not recruiting	`NCT03215368` - The Ma'Anshan Birth Cohort (MABC)
Recruiting	`NCT06083415` - Early Breast Growth in Girls Aged 6 to 8 Years in the Current Environmental Context	N/A

Clinical trials are conducted in a series of steps, called phases - each phase is designed to answer a separate research question.

Phase 1: Researchers test a new drug or treatment in a small group of people for the first time to evaluate its safety, determine a safe dosage range, and identify side effects.
Phase 2: The drug or treatment is given to a larger group of people to see if it is effective and to further evaluate its safety.
Phase 3: The drug or treatment is given to large groups of people to confirm its effectiveness, monitor side effects, compare it to commonly used treatments, and collect information that will allow the drug or treatment to be used safely.
Phase 4: Studies are done after the drug or treatment has been marketed to gather information on the drug's effect in various populations and any side effects associated with long-term use.

The Impact of Synergies of Indoor Air Pollutants on Childhood Health and Wellbeing — SynAir-Child

Clinical Trial Summary

Clinical Trial Description

Study Design

Related Conditions & MeSH terms