Treatment of Cantonese Speakers With Childhood Apraxia of Speech

Childhood Apraxia of Speech Clinical Trial

Official title:

Treatment of Cantonese Speakers With Childhood Apraxia of Speech

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT06385470
• Other study ID #: HSEARS20231112001
• Status: Recruiting
• Phase: N/A
• Start date: April 15, 2024
• Est. completion date: February 1, 2025

Study information

• Verified date: April 2024
• Source: The Hong Kong Polytechnic University
• Contact: Eddy Wong, PhD
• Phone: (852) 9834 0825
• Email: eddy-ch.wong[@]connect.polyu.hk
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The proposed study aims to investigate the efficacy of the Dynamic Temporal and Tactile Cueing treatment in Cantonese-English bilingual speakers with childhood apraxia of speech.

Description:

Four CE children with CAS will be recruited and receive two versions of the DTTC treatment (i.e., DTTC in English [DTTC-E] and DTTC in Cantonese [DTTC-C]). After the initial assessment and baseline probe sessions, all the participants will be randomly assigned to receive either DTTC-E or DTTC-C in the first 6-week treatment phase. Then, the between-treatment probe sessions will be conducted during a 2-week washout period. This will be followed by the second 6-week treatment phase, which will be the other version of DTTC. Post-treatment probe sessions will be conducted one week and one month after completion of the second treatment.

Participants' speech productions will be transcribed and evaluated based on their accuracy in phonemes, stress, and tone. Growth curve analysis (Mirman, 2014) will be conducted to examine the group differences in the outcome measures across the treatment sessions.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 4
• Est. completion date: February 1, 2025
• Est. primary completion date: August 1, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 3 Years to 11 Years

Eligibility

Inclusion Criteria:

• (1) 3;0 - 11;11 (years;months) years of age at treatment commencement;

• (2) speak both Cantonese and English: One caregiver one language for at least one year; speaking different languages at home versus school; and/or speak different languages at different times of day;

• (3) no concomitant developmental disorders including autism spectrum disorder;

• (4) no structural abnormalities that affect speech, such as cleft lip and/or palate;

• (5) no uncorrected vision impairment; and

• (6) no hearing loss;

• (7) CAS diagnosis confirmed by the research team based on the available diagnostic criteria in Cantonese speakers, which will be described in the next section

Exclusion Criteria:

-

Related Conditions & MeSH terms

• Apraxias
• Childhood Apraxia of Speech

Intervention

Behavioral:
• Dynamic Temporal and Tactile Cueing treatment
DTTC is a motor-based treatment designed for children with CAS who may have limited verbal output. It applies the principles of motor learning and focuses on speech movement gestures in the context of functional words and phrases. The participants will receive two versions of the DTTC treatment (i.e., DTTC in English [DTTC-E] and DTTC in Cantonese [DTTC-C]), where probe data will be collected before, during, between and after the treatment intervention.

Locations

Country	Name	City	State
Hong Kong	The Hong Kong Polytechnic University	Kowloon

Sponsors (3)

Lead Sponsor	Collaborator
The Hong Kong Polytechnic University	The University of Hong Kong, University of Vermont

Country where clinical trial is conducted

Hong Kong, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Phonemes accuracy	Participants' performance is probe sessions will be transcribed and analysed by an independent research assistant who has experience with Cantonese and English disordered speech will undergo training in phonetic transcription. The training will include practicing transcription of Cantonese and English speech of preschool children on standardized articulation tests. The accuracy of phonemes and the following aspects will be judged by the research assistant.	Change Before, Between, 1-week and 5-week post DTTC treatment
Primary	Stress accuracy	Participants' performance is probe sessions will be transcribed and analysed by an independent research assistant who has experience with Cantonese and English disordered speech will undergo training in phonetic transcription. The training will include practicing transcription of Cantonese and English speech of preschool children on standardized articulation tests. The accuracy of phonemes and the following aspects will be judged by the research assistant.	Change Before, Between, 1-week and 5-week post DTTC treatment
Primary	Tone accuracy	Participants' performance is probe sessions will be transcribed and analysed by an independent research assistant who has experience with Cantonese and English disordered speech will undergo training in phonetic transcription. The training will include practicing transcription of Cantonese and English speech of preschool children on standardized articulation tests. The accuracy of phonemes and the following aspects will be judged by the research assistant.	Change Before, Between, 1-week and 5-week post DTTC treatment