Symptom Clusters in Hong Kong Chinese Children With Blood Cancer

Child Clinical Trial

Official title:

Symptom Clusters in Hong Kong Chinese Children With Blood Cancer:: A Longitudinal Study

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04888195
• Other study ID #: SC_Blood_cancer
• Status: Recruiting
• Start date: September 1, 2021
• Est. completion date: September 1, 2024

Study information

• Verified date: April 2022
• Source: The Hong Kong Polytechnic University
• Contact: Ka Yan Ho, PhD
• Phone: 27666417
• Email: kyeva.ho[@]polyu.edu.hk
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Pediatric blood cancer is the most common childhood malignancy. Despite its survival has been substantially improved, children still have to pay a high price for numerous distressing symptoms resulted from chemotherapy. Previous studies related to symptom experiences mainly focus on individual symptoms, rather than on multiple symptoms. Understanding these distressing symptoms may help healthcare professionals to develop appropriate and effective interventions with the aims of alleviating symptom severity and thus promoting the child's psychosocial well-being and quality of life.

Description:

A longitudinal study design will be conducted. A sample of 120 patients age 5-17years, diagnosed with blood cancer but not yet receive any chemotherapy and able to communicate with Cantonese and read Chinese will be recruited in the pediatric oncology ward of Hong Kong Children's Hospital.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 120
• Est. completion date: September 1, 2024
• Est. primary completion date: September 1, 2024
• Accepts healthy volunteers: No
• Gender: All
• Age group: 5 Years to 17 Years

Eligibility

Inclusion Criteria:

• aged 5 - 17 years old

• diagnosed with blood cancer but not yet receive any chemotherapy

• able to communicate with Cantonese and read Chinese

Exclusion Criteria:

• who are scheduled to have concurrent cancer treatment

• with recurrent malignancy

• medical condition, or cognitive and learning problems in their medical records

Related Conditions & MeSH terms

• Child
• Hematologic Neoplasms
• Syndrome

Intervention

Other:
• Questionnaire
Participants will complete a set of validated questionnaires (TRSC-C and demographic sheet) before chemotherapy. They also have to complete the same questionnaires (TRSC-C) again within 1 week after the 1st, 2nd, 3rd, 4th , 5th and 6th courses of chemotherapy via telephone interview by our research assistants.

Locations

Country	Name	City	State
Hong Kong	Ka Yan Ho	Hong Kong	Hong Kong,China

Sponsors (1)

Lead Sponsor	Collaborator
The Hong Kong Polytechnic University

Country where clinical trial is conducted

Hong Kong, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The therapy-related symptom checklist for children (TRSC-C)	For measuring the occurrence and severity of symptoms experienced by patients aged 5-17 when they undergo cancer treatment.	Before chemotherapy
Primary	The therapy-related symptom checklist for children (TRSC-C) at 1-week	For measuring the occurrence and severity of symptoms experienced by patients aged 5-17 when they undergo cancer treatment.	At 1-week follow-up
Primary	The therapy-related symptom checklist for children (TRSC-C) at 1-month	For measuring the occurrence and severity of symptoms experienced by patients aged 5-17 when they undergo cancer treatment.	At 1-month follow-up
Primary	The therapy-related symptom checklist for children (TRSC-C) at 3-month	For measuring the occurrence and severity of symptoms experienced by patients aged 5-17 when they undergo cancer treatment.	At 3-month follow-up
Primary	The therapy-related symptom checklist for children (TRSC-C) at 6-month	For measuring the occurrence and severity of symptoms experienced by patients aged 5-17 when they undergo cancer treatment.	At 6-month follow-up
Primary	Demographic sheet	collect the background information of our subjects, including their age, gender, educational attainment, parents' marital status and religious belief	At baseline