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Clinical Trial Summary

This cluster-randomized trial aims to compare the impact of different delivery approaches to azithromycin distribution on coverage, costs, and feasibility outcomes. The investigators hypothesize that door-to-door delivery will have higher coverage and costs and similar feasibility and acceptability compared to fixed-point delivery.


Clinical Trial Description

Azithromycin distribution has been shown to reduce mortality in children 1-59 months. This trial aims to contribute evidence on viable approaches to implementation as high mortality countries consider this intervention to improve child survival. From a pool of eligible rural and peri-urban communities in the Dosso Region in Niger, 80 will be randomly selected and randomized to receive door-to-door or fixed-point delivery of a single dose of azithromycin distribution to children 1-59 months of age via community health workers biannually. Treatment coverage, costs and cost-effectiveness, and feasibility and acceptability will be compared by arm. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04774991
Study type Interventional
Source University of California, San Francisco
Contact Elodie Lebas, RN
Phone 5104232245
Email elodie.lebas@ucsf.edu
Status Recruiting
Phase Phase 4
Start date June 28, 2021
Completion date November 2024

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