Determination of ClotPro Paediatric Reference Range Study

Status Completed

Clinical Trial Summary

A new thromboelastometry analyser (ClotPro, Enicor GmbH, Munich, Germany) with improved technology was developed. This device has an improved new-generation viscoelastometric testing technique and enables the detection and assessment of factor deficiencies, low fibrinogen, platelet contribution (to whole blood coagulation), heparin and direct oral anticoagulants effects, fibrinolysis and antifibrinolytic drugs. This study aims to determine reference ranges for the ClotPro device for all paediatric age groups.

Clinical Trial Description

Viscoelastic testing as a relatively novel method to assess coagulation status appears favourable in reducing blood product transfusions. The tests are performed on whole blood instead of plasma, which saves time and gives a quick sight at the interaction between cellular and plasmatic clotting factors. Reviews of the literature suggest that transfusions of packed red blood cells (pRBC), plasma, and platelets are all decreased in patients whose transfusions were guided by viscoelastic tests rather than by clinical judgement or conventional laboratory tests. The benefits of viscoelastic coagulation monitoring have been described in many fields of surgery and intensive care. Current literature and a guideline for the treatment of massive haemorrhage in perioperative bleeding and trauma patients recommend the use of viscoelastic tests to guide haemostatic resuscitation. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT04190615
Study type	Observational
Source	National Institute of Children's Diseases, Slovakia
Contact
Status	Completed
Phase
Start date	December 17, 2019
Completion date	January 5, 2021

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT06315036` - Effects of Developmental Gymnastics on Preschoolers' Motor Skills	N/A
Active, not recruiting	`NCT05143294` - Conectar Jugando: Board Games in Elementary Classrooms (6-12 Years Old) to Improve Executive Functions	N/A
Completed	`NCT05267730` - Conectar Jugando: Board Games in Rural Elementary Classrooms (6-12 Years Old) to Improve Executive Functions	N/A
Completed	`NCT03680157` - Comparing Rater Reliability of Familiar Practitioners to Blinded Coders
Completed	`NCT00362076` - The Role of Motion in Infants' Ability to Categorize	N/A
Recruiting	`NCT05525962` - Vulnerability/Resilience Factors Influencing the Developmental Trajectories and Adaptive Methods of Children and Adolescents in Child Welfare System.
Completed	`NCT03232606` - Physical Activity of Asthmatic Children
Completed	`NCT05955755` - The Effect of Butterfly Vacuum Blood Collection Set and Standard Vacutanier Needle on the Level of Pain and Fear	N/A
Recruiting	`NCT04443855` - WASH Benefits Child Development Follow up	N/A
Not yet recruiting	`NCT06335524` - Infant-Maternal Partnership and Cognitive Training Study for Preterm Infants	N/A
Not yet recruiting	`NCT05783141` - Prebiotic Effects in Healthy Toddlers	N/A
Completed	`NCT02451059` - Reducing Socioeconomic Disparities in Health at Pediatric Visits	N/A
Completed	`NCT02539251` - Arabic Ages and Stages Questionnaire-III
Completed	`NCT02800616` - The Healthy Elementary School of the Future	N/A
Completed	`NCT02242539` - Tools to Improve Parental Recognition of Developmental Deficits in Children	N/A
Completed	`NCT03010306` - CASITA Intervention for Children at Risk of Delay in Carabayllo, Peru	N/A
Completed	`NCT01683565` - Preemie Tots: A Pilot Study to Understand the Effects of Prematurity in Toddlerhood	Phase 4
Completed	`NCT00989859` - Photo-Plethysmographic Camera to Monitor Heart Rate, Respiration Rate and Oxygen Saturation in Infants
Recruiting	`NCT00980733` - Efficacy of Micronutrient Fortified Yoghurt in School Children for Health Benefits	Phase 3
Terminated	`NCT04347707` - Building Regulation in Dual Generations	N/A