Cerebral Palsy Clinical Trial
Official title:
Reliability of Hammersmith Examination in Prediction of Neurological Outcomes In Preterm Infants - Observational Study (REHAPENO)
In this study workers are trying to test the correlation between Hammersmith Infant Neurological Examination and MRI brain/cranial ultrasound with early prediction of neurological developmental outcome of preterm neonates. This study is prospective cross-sectional collecting the data of patients according to daily standard medical practice
The primary aim of this study is to evaluate the neurobehavioural performance of infants born
preterm using the Hammersmith Infant Neurological Examination (HINE) in standard medical
practice and compare it with the gold standard MRI and ultrasound imagings. It would be
possible to check do we need to use all the 3 examinations or Hammersmith examination would
be enough reliable predictor. Secondary aim is to explore the relationships between MRI brain
/cranial us abnormalities and HINE at term-equivalent age in infants born preterm in
prediction of neurological outcome at 1 year of chronological age.
This study will be only single arm/single group. This group would receive the regular
practice of MRI, Ultrasound (US) and Hammersmith assessments. The 3 assessments would be
compared in relationships with the neonatal developmental outcomes (developmental
milestones).
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