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Chest Pain clinical trials

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NCT ID: NCT06348875 Not yet recruiting - Clinical trials for Coronary Artery Disease

Clinical Evaluation of Radiation Reduction for Optimized Safety

CERROS
Start date: June 15, 2024
Phase:
Study type: Observational

The primary objective of this study is to determine whether a reduced radiation protocol (RRP) in which angiograms are acquired at ultralow radiation doses and then processed using spatiotemporal enhancement software can produce similar quality angiographic images as compared with standard techniques.

NCT ID: NCT06325020 Not yet recruiting - Clinical trials for Coronary Artery Disease

Objective Risk Assessment in Patients With Possible Anginal Chest Pain Using Leading Technology

ORACLE
Start date: May 1, 2024
Phase:
Study type: Observational

The ORACLE study is an observational cohort study designed to explore the feasibility of providing an assessment of chest pain for patients with suspected angina within one working day of referral to specialist services. The primary objective is to determine the feasibility of delivering an objective assessment of risk for participants who have been referred by their primary care provider to the rapid access chest pain clinic with possible angina in a community setting using point of care and patient facing technologies within one working day of referral. Participants will complete a digital health questionnaire, at home, that asks about their risk factors for coronary artery disease, past medical history and their symptoms. Patients will then have a standard 12 lead ECG and perform their own personal ECG. They will then have high sensitivity cardiac troponin measured by point of care high sensitivity cardiac troponin assays as well as a core lab assay. The results of all of the above will allow patients to be started as low, intermediate or high risk for future cardiovascular events.

NCT ID: NCT06255769 Not yet recruiting - Myocardial Ischemia Clinical Trials

Diagnosis of Myocardial Ischemia With MCG Using SPECT as a Reference Standard

Start date: February 12, 2024
Phase:
Study type: Observational

This is a prospective clinical study aiming to investigate the efficacy of Magnetocardiography (MCG) in detecting myocardial ischemia in patients of a suspected non-ST-elevation-acute coronary syndrome (NSTE-ACS) by using Single photon emission computed tomography (SPECT) as the gold standard for determining the presence and severity of myocardial ischemia.

NCT ID: NCT06239974 Not yet recruiting - Chest Pain Clinical Trials

Randomised Controlled Trial of Vericiguat in Patients With Coronary Microvascular Dysfunction Causing Stable Chest Pain (V-COM)

Start date: August 1, 2024
Phase: N/A
Study type: Interventional

This is a randomised controlled trial to determine the effectiveness of Vericiguat to improve stress myocardial blood flow (MBF) and myocardial perfusion reserve as measured by cardiac magnetic resonance (CMR) imaging.

NCT ID: NCT06222320 Not yet recruiting - Rib Fractures Clinical Trials

Kinesiotaping Method for Rib Fractures

Start date: April 1, 2024
Phase: Phase 2/Phase 3
Study type: Interventional

Kinesiotaping is used as a physiotherapy method to reduce muscle pain. In this technique, kinesiotaping tapes are attached to the relevant parts of the body. Patients experience serious pain in rib fractures. Kinesiotaping technique can potentially reduce pain by contributing to external stabilization of the ribs. In this study, patients with isolated rib fractures will be divided into two groups. The first group will be treated with kinesiotaping technique and routine painkillers. The second group will receive routine painkiller treatment. Pain scores between both groups will be compared.

NCT ID: NCT05896826 Not yet recruiting - Clinical trials for Chest Pain, Acute Coronary Syndrome, Myocardial Infarction

Magnetocardiography in the Accurate Identification of Myocardial Infarction

Start date: June 1, 2023
Phase: N/A
Study type: Interventional

Magnetocardiography (MCG) is a promising noninvasive and accurate method for detecting myocardial infarction. Although progress has been made in this area, there is a lack of studies using up-to-date examination instruments for the calibration of MCG analysis. This is a prospective single-center study aiming to build accurate analytical models of MCG to detect myocardial infarction. Myocardial infarction are diagnosed by electrocardiogram, biomarkers (high-sensitivity cardiac troponin, etc), or non-invasive imaging (cardiac magnetic resonance or single-photon-emission tomography). Myocardial infarction is also quantified by cardiac magnetic resonance or single-photon-emission tomography. Healthy volunteers and chest pain patients who will receive electrocardiogram, biomarkers (high-sensitivity cardiac troponin, etc), or non-invasive imaging (cardiac magnetic resonance or single-photon-emission tomography) examination will be enrolled in this study.

NCT ID: NCT05857904 Not yet recruiting - Clinical trials for Coronary Artery Disease

Clinical Outcomes of CT-FFR Versus QFR-guided Strategy for Decision-Making in Patients With Stable Chest Pain

CONFIDENT
Start date: May 2023
Phase: N/A
Study type: Interventional

This study is a multicenter, prospective, blinded (blinding of clinical evaluators), randomized controlled, event-driven non-inferiority clinical trial. Eligible subjects who meet the inclusion criteria will be registered in the central randomization system and randomized in a 1:1 ratio to either the experimental group (CT-FFR guided group) or the control group (QFR guided group).

NCT ID: NCT05785923 Not yet recruiting - Chest Pain Clinical Trials

Low-Risk Chest Pain Echo Study

Start date: April 5, 2023
Phase: N/A
Study type: Interventional

Pilot study to assess if a bedside point-of-care echocardiogram performed on emergency department patients identified as low-risk chest pain prior to discharge significantly changes patient disposition or follow up instructions.

NCT ID: NCT05675267 Not yet recruiting - Clinical trials for Acute Coronary Syndrome

Interest of the HEART Score for the Management of Patients With Chest Pain in Emergency Department

HEART-SAU
Start date: January 10, 2023
Phase:
Study type: Observational

Chest pain is a frequent reason of consultation in emergency department. Emergency physician have to identify patients at high risk of Acute Coronary Syndrome from those presenting a lower risk.

NCT ID: NCT05649891 Not yet recruiting - Pneumonia Clinical Trials

Checklists Resuscitation Emergency Department

Start date: September 2023
Phase: N/A
Study type: Interventional

The study will systematically evaluate how an emergency manual-a collection of checklists and fact sheets-affects the performance of resuscitation teams during the management of priority one patients in an emergency department.