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Chest Pain clinical trials

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NCT ID: NCT00869245 Completed - Clinical trials for Acute Coronary Syndrome

Efficacy Evaluation of Observation Unit Cardiac Magnetic Resonance Imaging (MRI) in Patients With Intermediate Risk Acute Chest Pain

Start date: March 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the best way to evaluate patients with chest pain in the emergency department. It compares types of cardiac tests performed while receiving treatment in an observation unit. Patients will either undergo cardiac MRI testing or conventional care testing. Patients treated in the conventional care testing group will undergo the testing their doctor determines is best for them. All patients will undergo follow up to find out if they have had any heart related events.

NCT ID: NCT00855231 Completed - Clinical trials for Acute Coronary Syndrome

Diagnostic Accuracy of Multislice CT Angiography for Acute Chest Pain

ACUTE CT
Start date: July 2006
Phase: N/A
Study type: Observational

The ACUTE CT trial is designed to test whether the assessment of chest structures by high-resolution multislice computed tomography (CT) provides equivalent diagnostic accuracy for patient with acute chest pain or other potential cardiac symptoms as compared to a standard of care evaluation.

NCT ID: NCT00846469 Completed - Chest Pain Clinical Trials

Coronary Computed Tomography (CT) Angiography Versus Standard Therapy in the Emergency Room

Start date: July 2009
Phase: N/A
Study type: Interventional

The purpose of this study is to determine the usefulness of CCTA (Coronary Computed Tomography Angiography) in the emergency room setting to diagnose and predict the outcome of patients with chest pain who have a low to moderate risk of heart disease. And to also determine if the use of CCTA(Coronary Computed Tomography Angiography) is more cost effective (cost less) than the current standards of care treatments. To determine if patients who present to the emergency room w/low to moderate probability of having an ACS (Acute Coronary Syndrome) prefer CCTA (coronary computed tomography angiography)-based care compared to standard algorithm based care.

NCT ID: NCT00825435 Completed - Acute Chest Pain Clinical Trials

Coronary CT Angiography in Acute Chest Pain is a Cost Effective Risk Stratification Strategy

Start date: October 2008
Phase: Phase 3
Study type: Interventional

This study will evaluate the impact of adding coronary computed tomographic angiography (CTA) on health care costs for diagnosing patients with acute chest pain.

NCT ID: NCT00823563 Recruiting - Chest Pain Clinical Trials

Sex Differences in Coronary Pathophysiology

Start date: June 2007
Phase:
Study type: Observational

This is a research study evaluating possible causes of chest pain (or an anginal equivalent, such as fatigue resulting in a decrease in exercise tolerance, shortness of breath, or back, shoulder, neck, or jaw pain) in people with no evidence of significant coronary artery disease on their coronary angiogram (pictures of the blood vessels in the heart). The purpose of the research study is to determine if there is diffuse atherosclerosis (plaque) not appreciated by angiography, or if the coronary endothelium (lining of the blood vessels in the heart) and/or microcirculation (small vessels in the heart that are not easily seen with an angiogram) are not functioning properly in those who have chest pain (or an anginal equivalent), but normal coronary arteries on angiography. Specifically, we are interested if these findings are more common in women than men.

NCT ID: NCT00800527 Completed - Chest Pain Clinical Trials

Efficacy of Gabapentin in the Treatment of Chest Pain and Paresthesia in Patients With Sternotomy

Start date: November 2007
Phase: Phase 4
Study type: Interventional

In this study, the investigators aim to demonstrate the efficacy of gabapentin compared with diclofenac in the treatment of chronic non-ischemic chest pain and paresthesia of the patients with sternotomy and to elucidate the similarities of PCPP to neuropathic pain syndromes.

NCT ID: NCT00769574 Completed - Coronary Syndrome Clinical Trials

Assessment of New Biomarkers in the Management and Triage of Patients With Chest Pain and Suspicion of Non ST Elevation Acute Coronary Syndrome.

Start date: June 2008
Phase: N/A
Study type: Interventional

To assess diagnostic and prognostic value of new biomarkers in patients admitted for suspicion of non ST elevation acute coronary syndrome (NSTE ACS).

NCT ID: NCT00767065 Not yet recruiting - Acute Chest Pain Clinical Trials

Early Cardiac Computed Tomography (CT) In Patients Admitted With Acute Chest Pain

EXACCT
Start date: January 2009
Phase: N/A
Study type: Interventional

This is a randomised trial comparing early Cardiac Computed Tomography (CCT) to current standard practice for diagnosis of acute chest pain in patients at low to intermediate risk of having coronary artery disease (CAD), in a UK setting. We hypothesise that early CCT can reduce length of admission, reduce NHS costs and improve quality of life whilst being at least as safe as standard practice.

NCT ID: NCT00743197 Terminated - Chest Pain Clinical Trials

Women With Chest Pain and Normal Coronary Arteries Study

Start date: May 2008
Phase: N/A
Study type: Interventional

The purpose of this study is to compare the effectiveness of standard medical therapy versus usual care in women with chest pain, coronary endothelial dysfunction and unblocked coronary arteries. Coronary endothelial dysfunction (CED) is a condition in which the layers of cells around the heart do not function properly and is believed to be key factor in the development of atherosclerosis (fat deposits in arteries). In addition, CED is associated with an increased risk for future cardiovascular events, such as heart attack and stroke. A coronary angiogram allows physicians to see if any of the arteries in the heart are blocked, usually by fatty plaque. In many instances, angiograms in women experiencing chest pain do not show evidence of coronary disease (free of significant plaque build-up). Currently, there is no standard of care treatment plan for patients with normal coronary arteries, despite symptoms of chest pain, and as a result these patients may not receive medical treatment. However, these women often return to their physicians more than once with chest pain and go through a similar battery of tests.

NCT ID: NCT00736346 Recruiting - Panic Disorder Clinical Trials

Treatment of Panic Disorder Among Individuals Consulting Emergency Departments for Non Cardiac Chest Pain

MADONA
Start date: October 2005
Phase: N/A
Study type: Interventional

The purpose of this study is to assess the impact of three different treatment modalities on panic symptoms, quality of life and use of health services among individuals consulting an emergency department for non cardiac chest pain and having Panic Disorder.