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Clinical Trial Summary

This is a updated trial of NCT04188860 as a multi-center study. For recurrent or persistent advanced cervical cancer patients, the first-line chemotherapy was based on platinum. However, if they were refractory to platinum-based chemotherapy, there were no other more effective medications or treatment. The marketing of anti-PD-1 antibody has provided an opportunity of curative management. This single arm, open, phase II trial would recruit 122 eligible patients. A combination of anti-PD-1 antibody camrelizumab and albumin-bound paclitaxel would be given for all patients. The primary end is overall response rate (ORR). The second ends include progression-free survival, overall survival, disease control rate, remission duration, and adverse events. A molecular testing, mainly consisting of genomic analysis, will be carried in the oncologic tissues.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT05290935
Study type Interventional
Source Peking Union Medical College Hospital
Contact Lei Li, M.D.
Phone 10-139-1198-8831
Email lileigh@163.com
Status Recruiting
Phase Phase 2
Start date March 13, 2022
Completion date March 13, 2024

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