Impact of Dietary Fiber as Prebiotics on Chemotherapy-related Diarrhea in Patients With Gastrointestinal Tumors

Chemotherapy-related Diarrhea Clinical Trial

Official title: Impact of Dietary Fiber as Prebiotics on Chemotherapy-related Diarrhea in Patients With Gastrointestinal Tumors

Status Withdrawn

Clinical Trial Summary

This study evaluates longitudinal data associating changes in gut microbiota composition and diversity, defecation, performance status and adverse reactions in response to prebiotic fiber supplementation in patients with gastrointestinal cancer chemotherapy-related diarrhea. 120 adult participants , age 18 to 65 years, will be randomized into one of the two arms. Arm A (intervention group) will receive prebiotic fiber and loperamide hydrochloride capsule(a drug for standard treatment). Arm B will receive maltodextrin placebo and loperamide hydrochloride capsule.

Clinical Trial Description

n/a

Related Conditions & MeSH terms

• Chemotherapy-related Diarrhea
• Diarrhea
• Digestive System Neoplasms
• Gastrointestinal Neoplasms

• NCT number: NCT04447443
• Study type: Interventional
• Source: Second Affiliated Hospital, School of Medicine, Zhejiang University
• Status: Withdrawn
• Phase: N/A
• Start date: June 30, 2020
• Completion date: June 30, 2021