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Prediction of Getting Peripheral Neuropathy in Patients Treated With Bortezomib? — NFL-BIOPAIN  

Chemotherapy-induced Peripheral Neuropathy Clinical Trial

Official title:
Neurofilament Light Chain as Biomarker for Bortezomib-induced Peripheral Neuropathy

Clinical Trial Summary

Investigation of which patients treated with bortezomib that have increased risk of developing peripheral neuropathy.

Clinical Trial Description

The study aims to include 20 patients with multiple myeloma that are initiating bortezomib treatment. The patients must follow their normal treatment cycles while getting blood drawn during their treatment period however maximal 9 cycles. Blood is dawn before treatment initiation and approximately once per cycle in order to measure neurofilament light chain (NFL) before and during treatment. The primary outcome is to relate the level of NFL during treatment with the level at baseline and as a secondary outcome to relate the level of NFL to the cumulative dose of bortezomib. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05781425
Study type Observational
Source Odense University Hospital
Contact Per Damkier, ph.d.
Phone 26113790
Email Per.Damkier@rsyd.dk
Status Recruiting
Phase
Start date May 12, 2023
Completion date December 31, 2025
View Details
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