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Cannabidiol for Prevention of Chemotherapy-induced Peripheral Neuropathy — CINCAN-2  

Chemotherapy-induced Peripheral Neuropathy Clinical Trial

Official title:
A Phase II Trial of Cannabidiol for Prevention of Chemotherapy-induced Peripheral Neuropathy in Patients Receiving Oxaliplatin or Paclitaxel Based Chemotherapy

Clinical Trial Summary

This protocol describes a phase II trial investigating the efficacy of CBD in paclitaxel- and oxaliplatin-induced peripheral neuropathy. The trial uses multiple assessments such as validated PRO-questionnaires and multifrequency vibrometry.

Clinical Trial Description

Chemotherapy induced peripheral neuropathy (CIPN) is among the most feared side effects to cancer treatment. The development of CIPN can lead to omission or even discontinuation of antineoplastic drugs, possibly affecting efficacy of cancer treatment. There is a lack of knowledge about the natural course of CIPN and to this date, there are no available methods for the early detection of CIPN. With no effective prevention or treatment options, the condition has severe impact on patient quality of life and healthcare expenditure. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04582591
Study type Interventional
Source Zealand University Hospital
Contact
Status Active, not recruiting
Phase Phase 2
Start date March 3, 2021
Completion date August 30, 2023
View Details
See also
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