Clinical Trials Logo

Clinical Trial Summary

The COMMIT Study will assess the safety and effectiveness of FLX-787 in men and women with Charcot-Marie-Tooth disease (CMT) experiencing muscle cramps. Participants will be asked to take two study products during the course of the study. One of these study products will be a placebo.

Approximately 120 participants in 20 study centers across the United States are expected to take part. Participants will be in the study for approximately 3 months and visit the study clinic 3 times.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT03254199
Study type Interventional
Source Flex Pharma, Inc.
Contact
Status Terminated
Phase Phase 2
Start date October 16, 2017
Completion date July 27, 2018

See also
  Status Clinical Trial Phase
Recruiting NCT06203093 - Charcot-Marie-Tooth Disease (CMT) Biological Sample Collection for iPSC Generation and Biobanking
Recruiting NCT03782883 - The Impact of Charcot-Marie-Tooth Disease in the Real World
Recruiting NCT02979145 - Charcot-Marie-Tooth Disease (CMT) Infant Scale (INC-6611) N/A
Completed NCT02011204 - Study of Electrical Impedance Myography (EIM) in ALS N/A
Completed NCT00149045 - Follow up and Observation of Charcot Marie Tooth Disease in Families N/A
Completed NCT04786522 - Irisin Levels in Patients With Charcot-Marie-Tooth (CMT) Disease
Recruiting NCT05011006 - NT-3 Levels and Function in Individuals With CMT
Recruiting NCT05902351 - Natural History Study for Charcot Marie Tooth Disease
Terminated NCT03943290 - Extension Study to Evaluate the Long-Term Effects of ACE-083 in Patients With Facioscapulohumeral Muscular Dystrophy (FSHD) and Charcot-Marie Tooth (CMT) Disease Types 1 and X (CMT1 and CMTX) Phase 2
Active, not recruiting NCT04762758 - Phase III Trial Assessing the Efficacy and Safety of PXT3003 in CMT1A Patients Phase 3
Completed NCT02788734 - Patient Reported Outcomes Measures (PROM) in Carpal Tunnel Therapies in Patients With Inherited Neuropathies N/A
Recruiting NCT02532244 - Genetics of Pediatric-Onset Motor Neuron and Neuromuscular Diseases
Terminated NCT05827419 - Hearing and Balance Disorders in Peripheral Neuropathy
Terminated NCT03124459 - Study of ACE-083 in Patients With Charcot-Marie-Tooth Disease Phase 2
Terminated NCT03810508 - A Natural History Study of Charcot-Marie-Tooth 4J (CMT4J)
Recruiting NCT04010188 - A Registered Cohort Study on Charcot-Marie-Tooth Disease
Completed NCT00271635 - Ascorbic Acid Treatment in CMT1A Trial (AATIC) Phase 2
Completed NCT03715283 - Change in MUNIX in Patients With CMT1A Undergoing a Home Ankle Strengthening Program Versus Standard of Care N/A
Completed NCT02001038 - Survey of Current Management of Orthopaedic Complications in CMT Patients N/A
Not yet recruiting NCT01289704 - Treadmill, Stretching and Proprioceptive Exercise (TreSPE) Rehabilitation Program for Charcot−Marie−Tooth Neuropathy Type 1A (CMT1A) Phase 2/Phase 3