Preoperative Epidural Labor Analgesia and Postoperative Pain

Cesarean Section Clinical Trial

Official title:

The Influence of Preoperative Epidural Labor Analgesia on Postoperative Pain in Parturients Undergoing Cesarean Section: a Retrospective Analysis

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT03381690
• Other study ID #: Csec postop pain
• Status: Completed
• Start date: September 1, 2017
• Est. completion date: August 31, 2018

Study information

• Verified date: November 2019
• Source: Seoul National University Bundang Hospital
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

Parturients who undergo emergency Cesarean section (C-sec) after experiencing labor pain are likely to develop pain-induced central sensitization. The investigators hypothesized that those without epidural labor analgesia undergoing subsequent emergency C-sec would experience more severe postoperative pain or require more analgesia after C-sec compared to those with epidural labor analgesia. Thus, the investigators conducted this retrospective study by grouping parturients undergoing emergency C-sec after experiencing labor pain into two groups (epidural labor group and no epidural labor group) and those undergoing elective C-sec aimed to compare the effect of epidural labor analgesia on postoperative pain severity and analgesic consumption.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 222
• Est. completion date: August 31, 2018
• Est. primary completion date: August 31, 2018
• Accepts healthy volunteers: No
• Gender: Female
• Age group: 20 Years and older

Eligibility

Inclusion Criteria:

• Cesarean section(C-sec) under spinal anesthesia

Exclusion Criteria:

• Patients without accurate medical records

• Failure of epidural analgesia

Related Conditions & MeSH terms

• Cesarean Section
• Pain, Postoperative

Intervention

Procedure:
• Epidural labor analgesia
Epidural catheter was inserted for labor analgesia using an 18-gauge Tuohy needle and a 20 gauge epidural catheter. In our institute, for epidural labor analgesia, 10 ml bolus of 0.075% levobupivacaine mixed with fentanyl 2 µg/ml was administered and same regimen was continuously infused by patient-controlled epidural analgesia (infusion rate : 10 ml/hr, bolus : 4 ml, lockout time: 30 min).

Locations

Country	Name	City	State
Korea, Republic of	Seoul National University Bundang Hospital	Seongnam	Gyeonggi

Sponsors (1)

Lead Sponsor	Collaborator
Seoul National University Bundang Hospital

Country where clinical trial is conducted

Korea, Republic of, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	The change of numerical rating scale for postoperative pain		At postoperative 6h, 24h, 48h, and 72h.
Secondary	The change of postoperative analgesic consumption		At postoperative 6h, 24h, 48h, and 72h.