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Cesarean Section clinical trials

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NCT ID: NCT04884919 Recruiting - Cesarean Section Clinical Trials

Develop the First Aid Medical Supplies for Hemostasis and Bacteriostasis With Clinical Trial

Start date: May 10, 2019
Phase: N/A
Study type: Interventional

The current development of hemostatic and open wound infection care strategies will focus on enhancing the efficiency of hemostasis for internal bleeding, relieving pain, avoiding wound infection, and promoting wound healing. As the social environment changes, the demand for hemostatic techniques and wound healing is increasing. Thus, hemostatic techniques are needed to be integrated with functional functions for usual trauma care, and the wound care strategies that can inhibit and reduce infection while helping to facilitate wound healing are needed to be developed to ensure the safety of human life. Therefore, this trial aims to develop new biofiber hemostatic dressings for hemostasis and open wound care. The comparisons of hemostatic and antibacterial effects, hemostatic time, wound infection status, wound bacteria count, and wound adhesion situation obtained from this clinical trial are expected able to establish a better rapid hemostatic strategy and wound infection care strategy.

NCT ID: NCT04856735 Recruiting - Postoperative Pain Clinical Trials

Comparison of the Application of Lidocaine With Intraperitoneal Bupivacaine in Cesarian Operations Wound Infiltration

Start date: October 1, 2020
Phase: N/A
Study type: Interventional

Postoperative pain control is important to reduce morbidity and mortality, and this becomes even more important after cesarean delivery. Severe postpartum pain is associated with chronic pain, and the mother faces a 2.5-fold increased risk of chronic pain and a 3-fold increased risk of postpartum depression compared to mild ones Postoperative pain management is more difficult in the postpartum period. Because the main analgesics used are opioids that are excreted from milk and the newborn may be exposed to the side effects of these drugs . Therefore, multimodal approach is recommended in pain management. Surgical wound infiltration (LWI) of local anesthetics is an important component of multimodal analgesia . Some of the pain from surgery is caused by an inflammatory response to the surgical incision; therefore, reducing this inflammation can provide a better analgesia and also minimize side effects . Ease of use and safety of intraperitoneal local anesthetics (IPLA) has been demonstrated in studies and has become a useful alternative to opioid-based analgesic regimens for the treatment of acute postoperative pain. Investigators aim is to compare the effectiveness of LWI and IPLA applications on postoperative analgesia in women undergoing elective cesarean delivery under spinal anesthesia (SA). Investigators hypothesis, H0, was that there was no statistically significant difference between the three groups in the mean postoperative pain scores at the 24th hour during movement. H1 was a statistically significant difference between the mean postoperative pain scores at the 24th hour during the movement between the three groups. The primary aim of the study was pain scores during the postoperative 24th hour mobilization. Secondary outcome was total fentanyl consumption (µg) in the first postoperative 24 hours

NCT ID: NCT04799912 Recruiting - Cesarean Section Clinical Trials

Labor Induction in Low-risk Nulliparous Women at 39 Weeks of Gestation to Reduce Cesarean: A Randomized Trial of Induction Versus Expectant Management in France (FRENCH-ARRIVE)

FRENCH-ARRIVE
Start date: April 12, 2021
Phase: N/A
Study type: Interventional

The recent ARRIVE trial conducted in United States of America in 2014-2017 demonstrates that elective induction of labor at 39 weeks for nulliparous women did result in a significantly lower frequency of cesarean delivery with no significant differences of adverse perinatal outcomes. But the expected benefits of elective labor induction at 39 weeks have to be confirmed in other settings outside US before considering routine induction of labor for all low-risk nulliparous women at 39 weeks of gestation worldwide.

NCT ID: NCT04592926 Recruiting - Cesarean Section Clinical Trials

Pre-Insertion Ultrasound for Lateral-Position Spinal in Cesarean Delivery

Start date: April 22, 2021
Phase: N/A
Study type: Interventional

The purpose of this study is to evaluate the impact of lumbar ultrasound anatomic mapping using the Accuro device on the number of needle redirections, when performing spinal anesthesia in the lateral decubitus position on patients undergoing elective cesarean delivery.

NCT ID: NCT04450667 Recruiting - Cesarean Section Clinical Trials

Post Spinal Anesthesia Hypotension and Preoperative Hydration

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

Study of the impact of preoperative oral rehydration on the incidence of spinal anesthesia-induced hypotension for scheduled cesarean section.

NCT ID: NCT04399707 Recruiting - Analgesia Clinical Trials

Transcutaneous Electrical Nerve Stimulation for Post-Cesarean Pain Control

Start date: January 29, 2020
Phase: N/A
Study type: Interventional

Purpose of study is to evaluate the efficacy of transcutaneous electrical nerve stimulation (TENS) for post-operative pain control after a cesarean delivery compared to placebo and no TENS.

NCT ID: NCT04290208 Recruiting - Postoperative Pain Clinical Trials

A Comparison of IV Versus PO Acetaminophen Postoperatively for Opioid Consumption After Cesarean Section

Start date: August 22, 2019
Phase: Phase 4
Study type: Interventional

This randomized controlled study will compare narcotic consumption between two groups: patients that receive a perioperative dose of IV acetaminophen versus patients that receive a perioperative dose of oral liquid acetaminophen for scheduled cesarean section.

NCT ID: NCT04074005 Recruiting - Cesarean Section Clinical Trials

Incidence and Factors Involving Cesarean Delivery After Epidural Analgesia for Labor

Start date: September 1, 2019
Phase:
Study type: Observational

The rate of cesarean delivery after epidural analgesia for labor has not been reported in our institute. The aim of this study is to elucidate incidence of cesarean delivery in parturient whom received epidural analgesia. Besides, factors associated with the rate of cesarean delivery were studied.

NCT ID: NCT03905980 Recruiting - Cesarean Section Clinical Trials

Risk Factors for Primary Cesarean Section in Egypt

Start date: April 30, 2019
Phase:
Study type: Observational

women in their first pregnancy evaluated till delivery for associated risk factors for cesarean delivery

NCT ID: NCT03497364 Recruiting - Cesarean Section Clinical Trials

Combined Spinal-epidural Anesthesia for Cesarean Section Without Prophylactical Prehydration and Vasopressors

CSEAFCSWPPAV
Start date: May 1, 2018
Phase: N/A
Study type: Interventional

Hypotension is a common complication in pregnant women after spinal anesthesia and related with the dose of local anesthetic. Injecting small dose local anesthetic into subarachnoid space can decrease the incidence of hypotension, but increase the risk of incomplete analgesia and muscle relaxation. The investigators hypothesize there is an optimal dose of bupivacaine and ropivacaine for subarachnoid injection in pregnant women, which can cause enough anesthesia and obviously decrease the incidence of hypotension without prophylactical prehydration and vasopressors. To verify this hypothesis, full-term pregnant women who were scheduled for elective cesarean section were recruited.Combined spinal-epidural anesthesia was performed for pregnant women after written informed consents. The dose of bupivacaine or ropivacaine is small and depends on height of pregnant women. The blood pressure, heart rate, respiratory rate, SpO2 and fetal heart rate were recorded and the blood flow volume of uterine artery was monitored The sensory and motor block were evaluated. After delivery, umbilical blood samples were taken for blood gas analysis. APGAR scores and neurological behavior of infant were evaluated and recorded. In the intraoperative period, side-effects and requirement for sedation, epidural injection or general anesthesia were noted. The quality of anaesthesia (judged by the anaesthetist), the quality of muscle relaxation (judged by the surgeon) and the degree of intraoperative comfort (judged by the patient) were recorded as excellent, good, fair or poor.