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Vaginal Preparation With Chlorhexidine-alcohol vs. Povidine-iodine vs. Saline

Surgical Site Infection Clinical Trial

Official title:
The Effect of Vaginal Preparation With Chlorhexidine-alcohol vs. Povidine-iodine vs. Saline on Vaginal Bacteria Colony Counts in Pregnant Women

Clinical Trial Summary

The purpose of this study is to see whether chlorhexidine is superior to povidine-iodine vaginal antisepsis at reducing bacteria colony counts in pregnant women by comparing three groups: vaginal washing with chlorhexidine-alcohol, vaginal washing with povidine-iodine, and vaginal washing with saline alone.

Clinical Trial Description

This is a prospective trial of vaginal preparation (or vaginal cleansing/washing) on late preterm and term pregnancies admitted to Labor & Delivery unit for cesarean delivery with three arms. Randomization allocation would be performed in 1:1:1 fashion for vaginal preparation with chlorhexidine-alcohol, povidine-iodine, and saline washes. A saline wash group is included to determine if the act of cleansing the vagina with a sponge alone reduces bacterial colony counts. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03640507
Study type Interventional
Source Columbia University
Contact
Status Completed
Phase Phase 2/Phase 3
Start date October 1, 2018
Completion date June 14, 2019
View Details
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