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Cesarean Section Complications clinical trials

View clinical trials related to Cesarean Section Complications.

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NCT ID: NCT05704179 Completed - Quality of Life Clinical Trials

Evaluation of the Relationship Between Obstetric Comorbidity Index and Obstetric Quality of Recovery Score

Start date: January 20, 2023
Phase:
Study type: Observational

The goal of this prospective observational study is to learn about the correlation between obstetric comorbidity index and obstetric quality of recovery score in pregnant patients who undergo cesarean section. The main question aims to answer are: - Are there a correlation between the obstetric comorbidity index and the obstetric quality of recovery score? Can we predict the postoperative quality of recovery by calculating the obstetric comorbidity index before delivery? - What is the relationship between these scores with the type of anaesthesia given? Participants will answer an 11-question assessment scale to evaluate their recovery of quality in the postpartum period.

NCT ID: NCT05692245 Completed - Clinical trials for Cesarean Section Complications

Dexamethasone vs Ondansetron After Cesarean Delivery

Start date: March 30, 2023
Phase: Phase 4
Study type: Interventional

The goal of this clinical trial is to compare medications in women having a cesarean delivery. The main question it aims to answer are: • Which medication is better to use as a first-line prevention agent for nausea and vomiting Participants will rate their nausea, pain and other symptoms after surgery Researchers will compare two drugs, ondansetron and dexamethasone to see if the side effects of pain medications are improved after cesarean.

NCT ID: NCT05669300 Completed - Clinical trials for Cesarean Section Complications

Uterine Closure for Cesarean Section: a Novel Technique

Start date: December 1, 2022
Phase:
Study type: Observational

In here we want to describe a new technique to uterin closure at caesarean section which has been performed about 20 years by Bülent Yılmaz. The technique (we suggest the name of the technique as Yılmaz technique) provide less resuturing need when closing the uterus in cesarean section, bringing together better wound edges, providing more effective suture in thin uteruses, stopping active bleeding areas with the same suture, thus enabling to complete the surgery at low cost by using a single suture material in almost all cases. The aim of this study is to describe the technique and compare the blood loss of patients in caserean section between Yılmaz technique and single layer continue locked suturation .

NCT ID: NCT05664958 Completed - Clinical trials for Cesarean Section Complications

ESP Block for Post Cesarean Analgesia

Start date: April 17, 2023
Phase: Phase 4
Study type: Interventional

The purpose of this pilot study is to assess the analgesic efficacy of Erector Spinae Plane block (ESPB) with liposomal bupivacaine in women undergoing cesarean delivery and receiving a postoperative multimodal analgesic regimen as assessed by the dose of rescue postoperative opioids compared to a historical control group of women receiving the same multimodal regimen but with no truncal blocks. This will be a case control study with a prospective and a retrospective component. Women undergoing elective cesarean delivery under spinal or combined spinal epidural anesthesia will be approached to participate in the prospective open label component of the study. Cases will be matched in a 1:4 ratio by age, race, history of prior cesarean delivery, and insurance status with historical controls who received the same multimodal analgesic regimen but no truncal blocks. We plan to enroll 30 subjects for the prospective arm of the study and 120 for the retrospective arm.

NCT ID: NCT05553756 Active, not recruiting - Clinical trials for Cesarean Section Complications

Impact of Maltodextrin on Glycemic and Hemodynamic Management During Cesarean Section

MALTO-TC
Start date: April 13, 2020
Phase: N/A
Study type: Interventional

The goal is to evaluate the glycemic and hemodynamic stability in patients undergoing caesarean section in patients treated with maltodextrins two hours before the cesarean section

NCT ID: NCT05502146 Completed - Clinical trials for Cesarean Section Complications

Comparison of Two Different Norepinephrine Bolus Doses for Management of Spinal Anesthesia-Induced Maternal Hypotension

Start date: August 17, 2022
Phase: Phase 4
Study type: Interventional

In this study the investigators will compare two doses of norepinephrine bolus (6 mcg and 8 mcg) in management of maternal hypotensive episode after spinal block during cesarean delivery.

NCT ID: NCT05498025 Completed - Pain, Acute Clinical Trials

The Effect of a Charcoal Deactivation Pouch on Opioid Disposal After Cesarean Delivery

Start date: February 21, 2023
Phase: N/A
Study type: Interventional

Background: There is scarce literature investigating how patients dispose of unused opioid supplies after their cesarean postoperative pain has faded. The Office of the Surgeon General has identified research on the prevention of opioid use disorder area as well as research on the management of pain as a "Surgeon General Priority" that needs urgent investigation. Hypothesis: At least 33% of postpartum women discharged home with an opioid prescription and a drug deactivation pouch will use the pouch to dispose of remaining opioids within 30 days of delivery. Methods: This is a prospective single arm interventional pilot study.

NCT ID: NCT05488457 Not yet recruiting - Clinical trials for Cesarean Section Complications

Oxytocin Pharmacokinetics and Pharmacodynamics

Start date: July 1, 2024
Phase: Phase 2
Study type: Interventional

Oxytocin is the first-line drug to promote contraction of the uterus and prevent atony immediately after delivery. Nonetheless, unpredictable uterine atony refractory to oxytocin affects roughly 250,000 parturients annually in the U.S. and rates are increasing. This two-part study will measure the action of oxytocin at cesarean delivery. The first part will measure the pharmacokinetics of a single intravenous (IV) dose of deuterium-labeled oxytocin. The second part will measure the pharmacodynamics of all plasma oxytocin to see how concentrations correspond to the contractile effect on the uterus. After delivery of the fetus, study subjects will receive a bolus of IV deuterated oxytocin followed by an unlabeled oxytocin infusion. Venous blood samples drawn at multiple time points (within 1 hour after delivery) will be analyzed for plasma concentrations of labeled and unlabeled (endogenous + exogenous infused) oxytocin over time. Plasma concentrations will be compared with 0-10 uterine tone scores measuring uterine contraction strength, to describe the concentration-effect relationship. The goal of this study is to define both the pharmacokinetics and pharmacodynamics of oxytocin in parturients to help identify the cause(s) of failed first-line oxytocin therapy.

NCT ID: NCT05468125 Active, not recruiting - Hypotension Clinical Trials

Maternal Care Bundle to Attenuate Hypotension in Cesarean Section

Start date: August 1, 2022
Phase: N/A
Study type: Interventional

Cesarean Section (CS) is a common obstetric surgery that can be performed by both general or regional anaesthetic techniques. Hypotension is the most common complication of spinal anaesthesia, its incidence varying from 70% to 80 %, if severe, it can result in serious perinatal adverse outcomes, such as maternal nausea and vomiting, fetal acidosis and may be an important contributory factor for maternal death related to regional anaesthesia.

NCT ID: NCT05463146 Completed - Clinical trials for Cesarean Section Complications

Effects of Deep Breathing Excer. With & Without PMR on Post C Section LBP, QOS & PA

Start date: January 20, 2022
Phase: N/A
Study type: Interventional

To find out the Effects of deep breathing exercises with and without Progressive Muscle Relaxation Technique on Post Cesarean Section low back Pain, Quality of Sleep and Physical Activity