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Cesarean Scar Pregnancy clinical trials

View clinical trials related to Cesarean Scar Pregnancy.

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NCT ID: NCT05839574 Completed - Clinical trials for Cesarean Scar Pregnancy

Letrozole add-on in the Treatment of Cesarean Scar Pregnancy

Start date: January 1, 2021
Phase: N/A
Study type: Interventional

It is hypothesized that the inhibition of estradiol production by letrozole may interfere with physiological effects of progesterone necessary to maintain the pregnancy. There is no reference treatment of cesarean scar pregnancy (CSP) as the limited number of cases precludes the extrapolation of results. In our center we successfully use two-step treatment with methotrexate (MTX) followed by hysteroscopic removal of products of conception (POC). The time in between is needed to achieve a decrease in the trophoblast's vital potential (B-hCG fall) and its vascularization. Additional administration of letrozole could further reduce the vital potential of the pregnancy, eliminating the need for another dose of MTX, resulting in faster healing and lower rate of complications.

NCT ID: NCT04955028 Completed - Clinical trials for Cesarean Scar Pregnancy

MRI in Predicting Intraoperative Massive Hemorrhage for Cesarean Scar Pregnancy

Start date: January 27, 2015
Phase:
Study type: Observational

MRI features and clinical characteristics to predict massive hemorrhage during hysteroscopic treatment of CSP, and to aid the choice of treatment.

NCT ID: NCT04379219 Recruiting - Clinical trials for Cesarean Scar Pregnancy

Surgery Alone Versus Methotrexate Before Surgery in Cesarean Scar Pregnancy

Start date: December 1, 2019
Phase: Phase 4
Study type: Interventional

There are no universal treatment guidelines available. The ultimate purpose of the management of CSP is to simultaneously remove the pregnancy and successfully preserve the woman's fertility (Gonzalez & Tulandi, 2017). A variety of medical and surgical treatment modalities for CSP have been reported; however, most of these are based on low‐level evidence(Sun et al., 2019).

NCT ID: NCT03218059 Not yet recruiting - Menstruation Clinical Trials

Outcome After MTX & Transvaginal Surgery or UAE & Uterine Curettage in Patients With Cesarean Scar Pregnancy

Start date: July 15, 2017
Phase: N/A
Study type: Interventional

Cesarean scar pregnancy (CSP)is one of the more serious complications of pregnancies that occur after a prior cesarean delivery. No clinical guidelines have been issued for the management of CSP. More than 30 treatment methods are reported to be used in managing CSP. However, which management can achieve better clinical effects remains unknown. Therefore, this prospective study is designed to compare the outcome between MTX + transvaginal surgery and UAE + D&C in the treatment of CSP.