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Cesarean Delivery clinical trials

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NCT ID: NCT03455660 Completed - Cesarean Delivery Clinical Trials

A Retrospective Comparison of Neonatal Acid-base Status After CD Before January, 2015 and After January, 2016

Start date: December 2014
Phase: N/A
Study type: Observational

The objective is to retrospectively gather peri-operative data on neonatal outcomes, primarily neonatal acid-base status, based on umbilical cord gas analysis, for the 23 months preceding and 23 months following the conduct of the "tilt versus supine study". The investigators hypothesize that there will be no difference in mean neonatal umbilical artery base excess in neonates delivered by cesarean section during the period before and after conduct of the study, for elective, urgent and emergent deliveries.

NCT ID: NCT03402685 Completed - Clinical trials for Cesarean Section Complications

Continuous Non-invasive Blood Pressure Measurement in C-section

ClearBirth
Start date: May 17, 2018
Phase: N/A
Study type: Interventional

The caesarean section is a frequently performed procedure in obstetrics and accounts for about 30% of all births in Germany. 55% to 68% of all caesarean sections are performed under spinal anesthesia. A possible side effect of spinal anesthesia is arterial hypotension with a prevalence of 70% to 80%. A placental hypoperfusion in the context of a reduced preload due to hypotension can reduce the fetal outcome. Early diagnosis and treatment of the hypotensive episode could reduce and at best prevent increased fetal morbidity. Due to their invasiveness due to the necessity of puncturing a distal artery of the extremity and the insertion of a catheter, established continuous blood pressure measurement procedures have disadvantages such as potential circulatory disorders of the hand, infections, bleeding and thrombosis and are therefore often not indicated in the context of an elective sectio. Non-invasive procedures such as NIBP, however, are discontinuous and may make a timely diagnosis of hypotension more difficult and delay therapy. The ClearSightTM system, which allows a continuous non-invasive blood pressure measurement, has been used in hip and knee joint surgery. There, a good correlation with invasive blood pressure measurements was found, particularly with regard to systolic and mean arterial pressure. An application in obstetrics has not yet been investigated. Due to the continuous measurement provided by ClearSightTM, continuous monitoring of blood pressure appears to be ensured, so that a faster reaction to previously undetected fluctuations in blood pressure can be expected compared to interval measurement.

NCT ID: NCT03389139 Completed - Clinical trials for Cesarean Delivery Affecting Newborn

Cerebral and Renal Oxymetry and Anesthetic Techniques in Newborns

Start date: January 2017
Phase: N/A
Study type: Interventional

Neonatal adaptation to extrauterine life has many physiological changes in neonatal organ systems. These adaptative changes may be affected such as type of delivery and anesthesia management at birth. near infrared spectroscopy (NIRS) is a popular non-invasive method that can be used in newborns thus monitorize tissue oxygenation regularly. In this study we have purposed to compare the effects of general anesthesia versus spinal anesthesia on newborn's cerebral and renal oxygenation in elective cesarean operations

NCT ID: NCT03349151 Completed - Clinical trials for Postoperative Nausea and Vomiting

Postoperative Results of Early Versus On-demand Maternal Feeding After Cesarean Delivery

Start date: November 19, 2017
Phase: N/A
Study type: Interventional

To compare early versus on demand maternal feeding after cesarean delivery regarding gastrointestinal complaints and patient's satisfaction.

NCT ID: NCT03336541 Completed - Clinical trials for Postpartum Depression

Low-dose Ketamine and Postpartum Depression in Parturients With Prenatal Depression

Start date: November 23, 2017
Phase: Phase 4
Study type: Interventional

Postpartum depression is common in mothers early after childbirth and produces harmful effects not only on mothers, but also on infants and young children. Parturients with prenatal depression are at increased of postpartum depression. Low-dose ketamine can be used for antidepressant therapy. We hypothesize that low-dose ketamine has a therapeutic effect on parturients with prenatal depression. This study is designed to investigate whether low-dose ketamine administered during cesarean delivery can decrease the incidence of postpartum depression in parturients with prenatal depression.

NCT ID: NCT03321175 Completed - Clinical trials for Cesarean Section; Complications, Wound, Hematoma

Evaluation the Impact of Subcutaneous Irrigation on Wound Complications

Start date: October 23, 2017
Phase: N/A
Study type: Interventional

to evaluate the effect of subcutaneous irrigation on wound complications

NCT ID: NCT03236324 Completed - Cesarean Delivery Clinical Trials

Transversalis Fascia Plane Blocks for Analgesia Post-cesarean Delivery

Start date: September 22, 2017
Phase: Phase 2
Study type: Interventional

The aim of this study is to assess the efficacy of a bilateral TFP block in parturients undergoing cesarean delivery (CD) by evaluating postoperative opioid consumption and numeric rated pain scores in two groups (TFP block with saline (control) and TFP block with local anesthetic (treatment)). Women (American Society of Anesthesiologists physical status Class 1-3) at term gestation with singleton pregnancies undergoing an elective CD under spinal anesthesia at the South Health Campus will be consented to participate in the study. Patients will be randomly assigned using a computer-generated table of random numbers to two groups. Group allocations will be concealed. All patients will receive spinal anesthesia with spinal Morphine according to our institutional protocol. At the end of surgery, randomized patients will receive either ultrasound-guided bilateral TFP blocks with 0.25% bupivacaine with 2.5 mcg/ml epinephrine 40 ml total or maximum 2.5 mg/kg (Group 1) or 40 mL saline (Group 2) by 2 anesthesiologists experienced in performing this block.

NCT ID: NCT03150641 Completed - Cesarean Delivery Clinical Trials

Delayed Cord Clamping at Term Cesarean

Start date: September 18, 2017
Phase: N/A
Study type: Interventional

The purpose of this research study is to find out how delaying cutting the umbilical cord until one minute after delivery of the baby during a cesarean impacts the amount of blood the mother loses during surgery. The study will also examine the benefits to the newborn from delayed cord clamping during cesarean.

NCT ID: NCT03136159 Completed - Clinical trials for Cesarean Section; Complications, Wound, Dehiscence

The Role of Antimicrobial Foam Dressing in Prevention of Cesarean Section Wound Complications

Start date: July 24, 2017
Phase: N/A
Study type: Interventional

Post-cesarean section wound infections are responsible for longer hospital stays, readmissions, and ultimately, increased costs to the healthcare system. Silver-containing dressings may prevent wound infections. The purpose of the current study is to determine if the use of a silver-impregnated dressing decreases the occurence of wound infection following cesarean delivery.

NCT ID: NCT03063853 Completed - Clinical trials for Cesarean Section; Wound, Infection (Following Delivery)

Removal of Surgical Staples After Cesarean Delivery. Randomized Control Trial.

ROCD
Start date: February 1, 2017
Phase: N/A
Study type: Interventional

The optimal choice of skin closure at cesarean delivery has not yet been determined. This study aim to study the wound complications and scar healing after Surgical staples removal at postoperative day 4 and day 8 . A randomized control trial.