Uterine Neoplasms Clinical Trial
Official title:
A Pilot Study of Conformal Intensity Modulated Radiation Therapy (IMRT) for Gynaecological Cancer Patients Not Suitable for Intracavitary Brachytherapy Boost (GY03.2)
Standard treatment for gynecological cancer is radiation therapy in two phases; whole pelvic
radiation and then an internal radiation boost, also called a brachytherapy boost, to treat
any remaining tumour.
The purpose of this study is to test an alternative radiation boost treatment called
conformal intensity modulated radiation therapy or IMRT. Currently, we do not have complete
information on the overall effectiveness of IMRT compared to brachytherapy or conformal
radiotherapy. We know that IMRT allows the radiation beams to be more accurately focused on
the tumor, thereby sparing more normal tissue from radiation damage and lowering risks of
side effects. We are investigating the extent to which IMRT can be used to protect normal
tissues in patients with cervix, uterine or vaginal cancer from the radiation beams and how
much the side effects of radiation are reduced.
n/a
Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Treatment
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