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Cervical Spinal Cord Injury clinical trials

View clinical trials related to Cervical Spinal Cord Injury.

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NCT ID: NCT05035823 Active, not recruiting - Clinical trials for Spinal Cord Injuries

COMMAND Early Feasibility Study: Implantable BCI to Control a Digital Device for People With Paralysis

Start date: April 27, 2022
Phase: N/A
Study type: Interventional

The Synchron motor neuroprosthesis (MNP) is intended to be used in subjects with severe motor impairment, unresponsive to medical or rehabilitative therapy and a persistent functioning motor cortex. The purpose of this research is to evaluate safety and feasibility. The MNP is a type of implantable brain computer interface which bypasses dysfunctional motor neurons. The device is designed to restore the transmission of neural signal from the cerebral cortex utilized for neuromuscular control of digital devices, resulting in a successful execution of non-mechanical digital commands.

NCT ID: NCT04995796 Completed - Tetraplegia Clinical Trials

Testing the Decision Aid: Supporting Patient Decisions About Upper Extremity Surgery in Cervical SCI

Start date: December 1, 2021
Phase: N/A
Study type: Interventional

Purpose: The objective of this study is to assess a newly created decision support intervention (DSI) or decision aid (DA) for people with spinal cord injury (SCI) to learn about and consider upper extremity reconstructive surgery to help them choose a course of treatment that most aligns with their values.

NCT ID: NCT04949971 Recruiting - Clinical trials for Cervical Spinal Cord Injury

A Comparative Study of High and Low Tidal Volume in Preventing Hypoxemia in Patients With Mechanical Ventilation After Cervical Spinal Cord Injury

Start date: April 3, 2021
Phase:
Study type: Observational

This study in order to best tidal volume mechanical ventilation in patients with cervical spinal cord injury (sci) as the research point, through higher low volume Settings to find the difference of two groups of patients to prevent the incidence of hypoxemia, to find suitable Settings, tidal volume in patients with lower mechanical ventilation in patients with cervical spinal cord injury (sci) the incidence of pulmonary complications, live less intensive care unit (ICU).

NCT ID: NCT04855838 Recruiting - Dysphagia Clinical Trials

Dysphagia After Anterior Cervical Spine Surgery

Start date: December 17, 2020
Phase: N/A
Study type: Interventional

The purpose of this research project is to investigate the incidence of impaired swallowing (dysphagia) after anterior cervical spine surgery (ACSS) and to study the long-term effect of dysphagia on nutritional status 12 ± 3 months later. Furthermore, to investigate the effect of a new rehabilitation method for dysphagia among individuals with swallowing dysfunction after ACSS.

NCT ID: NCT04815967 Active, not recruiting - Multiple Sclerosis Clinical Trials

Efficacy and Safety Study of MYOBLOC® in the Treatment of Adult Upper Limb Spasticity

Start date: November 16, 2021
Phase: Phase 2/Phase 3
Study type: Interventional

Phase 2/3, randomized, double-blind, placebo-controlled, single-treatment, multicenter trial assessing the efficacy and safety of MYOBLOC for the treatment of upper limb spasticity in adults followed by an open-label extension safety trial.

NCT ID: NCT04777149 Completed - Clinical trials for Spinal Cord Injuries

Random Noise Stimulation to Enhance Cortical Drive & Improve Hand Function

Start date: April 12, 2021
Phase: N/A
Study type: Interventional

Cervical spinal cord injury (SCI) results in hand and arm function impairments and decreased independence in performance of daily activities such as bathing, eating, dressing, writing, or typing. Recent approaches that involve the application of non-invasive brain stimulation have the potential to strengthen the remaining connections between the brain and the spinal cord for improved hand function. Combining brain stimulation with performing upper limb functional tasks may further increase the ability of individuals with tetraplegia to use their hands. The purpose of this study is to investigate if "random noise", a special type of brain stimulation that most people cannot feel, can be used to enhance upper limb function in individuals with spinal cord injury. Specifically, the investigators will examine if a combined treatment protocol of random noise and fine motor training results in greater improvements in motor and sensory hand function compared to fine motor training alone.

NCT ID: NCT04688229 Not yet recruiting - Acute Stroke Clinical Trials

Motor Recovery Training for Hand and Digits in Stroke and SCI

Start date: October 20, 2021
Phase: N/A
Study type: Interventional

This study will use evaluate a hand therapy device training isolated finger control with engaging video gaming technology to facilitate hand and digit recovery in patients with acute stroke and cervical spinal cord injury. This study will randomize patients to either standard rehabilitation care with added study-related motor training or standard rehabilitation care alone.

NCT ID: NCT04183998 Completed - Clinical trials for Traumatic Brain Injury

Restorative Neuromodulation for Upper Extremity Functions

Start date: May 1, 2019
Phase: N/A
Study type: Interventional

The objective of this research study is to find the efficacy of trans-spinal electrical stimulation, a non-invasive neurostimulation method to modulate the functions of spinal cord neurocircuits, on improving upper-extremity functions such as reaching and grasping in individuals suffering with traumatic brain injury (TBI) or cervical spinal cord injury (SCI); and to find the physiological changes in the neuromuscular systems after this new intervention with high-resolution electrophysiology and biomedical imaging.

NCT ID: NCT04179799 Completed - Clinical trials for Cervical Spinal Cord Injury

Diaphragm Pacing in Individuals With Spinal Cord Injuries

Start date: January 10, 2020
Phase:
Study type: Observational

This project will evaluate the effects of intramuscular diaphragm stimulation (pacing) and test the hypothesis that diaphragm pacing enhances neuromuscular diaphragm activation and respiratory function in adults with cervical spinal cord injuries (C-SCIs). The investigators will test the hypothesis by recording activity of the diaphragm from intramuscular pacing electrodes and conduct respiratory assessments in adults with intramuscular diaphragm pacing electrodes following acute, traumatic C-SCIs.

NCT ID: NCT04041063 Recruiting - Clinical trials for Spinal Cord Injuries

Rehabilitation and Cortical Remodeling After Surgical Intervention for Spinal Cord Injury

Start date: July 26, 2019
Phase: Phase 2
Study type: Interventional

The aim of this study is to determine the effects of rehabilitation on dexterous hand movements and cortical motor map changes in tetraplegic patients following nerve transfer surgery. The working hypothesis is that robot-assisted, intensive rehabilitation will support the return of hand and arm function and strengthen the cortical representations of targeted muscles. The investigators will assess this through TMS mapping and clinical measures of hand and arm function.