Clinical Trials Logo
  1. Home
  2. Cervical Myelopathy
  3. NCT05446259
  4. Details
NCT05446259 Clinical Trial

Degenerative Cervical Myelopathy Repository

Cervical Myelopathy Clinical Trial

— DCM  

Official title:
Development of a Predictive Outcome Model for Patients With Degenerative Cervical Myelopathy Using Objective Functional and Biological Measures.

Clinical Trial Details — Status: Recruiting

Administrative data
NCT number NCT05446259
Other study ID # 78340
Secondary ID
Status Recruiting
Phase
First received
Last updated
Start date July 13, 2022
Est. completion date May 2028

Study information
Verified date July 2023
Source University of Kentucky
Contact Francis Farhadi, MD, PhD
Phone 859-562-0247
Email francis.farhadi@uky.edu
Is FDA regulated No
Health authority
Study type Observational [Patient Registry]

Clinical Trial Summary

To create a research repository of patients with known degenerative cervical myelopathy (DCM) and a control cohort of subjects who have non-myelopathic spinal disease. This repository will be used to assess functional and/or biological measures that may allow for improved prediction of symptomatic progression and response to treatment in patients with DCM. In addition, this repository will be used to develop a risk assessment scale to accurately predict functional outcomes following operative management of DCM.

Recruitment information / eligibility
Status Recruiting
Enrollment 245
Est. completion date May 2028
Est. primary completion date June 2027
Accepts healthy volunteers No
Gender All
Age group 18 Years to 100 Years
Eligibility Inclusion Criteria: - Diagnosis of degenerative cervical myelopathy - Diagnosis of cervical degenerative disease without myelopathy Exclusion Criteria: - None outside or diagnostic requirements and age limits.

Study Design

Related Conditions & MeSH terms

Intervention

Other:
• Standard clinical care procedures and outcome measurements.
Standard of care surgical interventions, imaging impressions, laboratory results, and outcome measurements will be collected and analyzed.

Locations
Country Name City State
United States University of Kentucky Lexington Kentucky

Sponsors (1)
Lead Sponsor Collaborator
University of Kentucky

Country where clinical trial is conducted

United States, 

Outcome
Type Measure Description Time frame Safety issue
Primary Data comparison between DCM and control groups This study is to determine biomarkers associated with DCM and analyze objective clinical measures to determine more predictable and potentially effective treatments for patients diagnosed with cervical myelopathy. 2 years
See also
  Status Clinical Trial Phase
Completed NCT03695848 - Prognostic Value of DTI and fMRI of Cervical Myelopathy
Terminated NCT00974623 - Bone Graft Materials Observational Registry N/A
Enrolling by invitation NCT04381663 - CSS-Assessing the Course of Degenerative Cervical Spinal Stenosis Using Functional Outcomes
Recruiting NCT05163639 - Spinal Cord Associative Plasticity Study Early Phase 1
Recruiting NCT05183971 - Proprioceptive Deficits in Degenerative Cervical Myelopathy
Completed NCT02125981 - The Study About the Efficacy of Oral Limaprost After Surgery for Cervical Myelopathy Phase 3
Withdrawn NCT04315090 - Post-surgical Outcomes Measure Using the ERAS Protocol for Posterior Cervical Decompression and Fusion
Not yet recruiting NCT05099627 - Machine Learning Diagnosis and Prediction for Cervical Myelopathy
Completed NCT04173923 - Long Term Follow-up of Cervical Myelopathy Inpatients Treated With Integrated Complementary and Alternative Medicine
Enrolling by invitation NCT05066711 - NuVasive® ACP System Study
Enrolling by invitation NCT04770571 - Posterior Cervical Fixation Study
Terminated NCT02758899 - Diabetes and Glycosylation in Cervical Spondylosis
Completed NCT04962256 - ERAS in Posterior Approach of Cervical Spine Operation
Completed NCT04320043 - Adjacent Segment Disease After Anterior Cervical Decompression Surgery
Completed NCT03304236 - Motion Analysis of the Myelopathy Hand: New Insight Into the Classical Sign
Completed NCT02842775 - Clinical Evaluation and Rehabilitation System for Dynamic Balance Control in Cervical Myelopathy Patients N/A
Completed NCT01027546 - Effect of Tranexamic Acid on Reducing Postoperative Blood Loss in Cervical Laminoplasty N/A
Recruiting NCT03950349 - FUSION EVALUATION AFTER ANTERIOR CERVICAL DISCECTOMY AND FUSION WITH STAND ALONE LOCKING CAGE WITH BLADE HRCC®
Recruiting NCT04968639 - The Characteristic of Axial Pain and EEG Analysis of Patients After Laminoplasty
Enrolling by invitation NCT05762055 - Prospective Comparative Analysis of ACDF vs Fusion Interbody Cages With nanoLOCK Osseointegrative Technology N/A