Clinical Trials Logo

Clinical Trial Summary

Proprioceptive deficits in degenerative cervical myelopathy (DCM) is a progressive neurological deficits in somatosensory and motor function which affects the body balance and motor control. DCM usually presents with body incoordination, hand clumsiness and gait disturbance associated with proprioceptive dysfunction that hinders the physical performance and functions. In this study, a non-invasive assessment protocol on proprioception will be developed for detecting subtle proprioceptive deficits at the early stage of disease through simple Physical Performance Tests for population older than 45. By adopting the physical performance tests as the diagnostic predictors of DCM, we aim to avoid the development of devastating consequences and disabilities.

Clinical Trial Description

DCM is a chronic insidious disease, one of the most disabling orthopaedic conditions, which involves compression of the spinal cord by the surrounding structures in cervical spinal region. It characterizes with progressive neurological deficits in body coordination, hand clumsiness and gait disturbance as the preliminary symptom which may cause by proprioceptive dysfunction . Physical performance and function hinder patients' hand clumsiness, gait disturbance and body imbalance. The incoordination between body, upper limbs and lower limbs will be resulted from proprioceptive deficits caused by spinal cord compression. By adopting the Proprioceptive Functional Analysis System (PFAS), proprioceptive deficits over the core body joints and peripheral joints could be tested during Activity of Daily Living (ADL) with reference to normal subjects' performance. All subjects will be tested by the PFAS and Physical Performance Tests. The idea of regional proprioceptive deficit will be incorporated in the assessment protocol for DCM to facilitates a breakthrough from the traditional DCM functional evaluation. In developing a non-invasive assessment protocol to assess proprioceptive deficit, we aim to detect subtle proprioceptive deficit from the tests, especially at the very early stage of disease. We target to demonstrate the validity of Physical Performance Tests are evenly high as that of the advanced technology, PFAS. Consequently, by adopting the valid Physical Performance Tests in health screening scheme for population older than 45 within the community can serve as an early diagnostic parameter of DCM and avoid delayed treatment leading to devastating consequences and disabilities. ;

Study Design

Related Conditions & MeSH terms

NCT number NCT05183971
Study type Observational
Source The University of Hong Kong
Contact Karlen Ka Pui Law, M. Phil
Phone 852-29740531
Email [email protected]
Status Not yet recruiting
Start date January 31, 2022
Completion date September 30, 2036

See also
  Status Clinical Trial Phase
Recruiting NCT03695848 - Prognostic Value of DTI and fMRI of Cervical Myelopathy
Terminated NCT00974623 - Bone Graft Materials Observational Registry N/A
Enrolling by invitation NCT04381663 - CSS-Assessing the Course of Degenerative Cervical Spinal Stenosis Using Functional Outcomes
Recruiting NCT05163639 - Spinal Cord Associative Plasticity Study N/A
Not yet recruiting NCT04545983 - Long-term Follow-up Motion Analysis of ACD Versus ACDA N/A
Recruiting NCT02125981 - The Study About the Efficacy of Oral Limaprost After Surgery for Cervical Myelopathy Phase 3
Withdrawn NCT04315090 - Post-surgical Outcomes Measure Using the ERAS Protocol for Posterior Cervical Decompression and Fusion
Not yet recruiting NCT05099627 - Machine Learning Diagnosis and Prediction for Cervical Myelopathy
Completed NCT04173923 - Long Term Follow-up of Cervical Myelopathy Inpatients Treated With Integrated Complementary and Alternative Medicine
Not yet recruiting NCT04770571 - Posterior Cervical Study
Terminated NCT02758899 - Diabetes and Glycosylation in Cervical Spondylosis
Recruiting NCT04962256 - ERAS in Posterior Approach of Cervical Spine Operation
Completed NCT04320043 - Adjacent Segment Disease After Anterior Cervical Decompression Surgery
Completed NCT03304236 - Motion Analysis of the Myelopathy Hand: New Insight Into the Classical Sign
Not yet recruiting NCT05066711 - NuVasive® ACP System Study
Completed NCT02842775 - Clinical Evaluation and Rehabilitation System for Dynamic Balance Control in Cervical Myelopathy Patients N/A
Completed NCT01027546 - Effect of Tranexamic Acid on Reducing Postoperative Blood Loss in Cervical Laminoplasty N/A
Recruiting NCT04968639 - The Characteristic of Axial Pain and EEG Analysis of Patients After Laminoplasty
Recruiting NCT03842072 - The Collar Post Anterior Cervical Spine Surgery Study N/A