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Fenofibrate in Patients With Cervical Intraepithelial Neoplasia and Invasive Cervical Carcinoma

Cervical Intraepithelial Neoplasia Clinical Trial

Official title:
Window of Opportunity Trial of Fenofibrate in Patients With High-grade Cervical Intraepithelial Neoplasia and Invasive Cervical Carcinoma

Clinical Trial Summary

Normally, p53 helps prevent tumors from forming in the body. Early studies have shown that Fenofibrate, a cholesterol-lowering drug, can restore normal function to p53 and can change the metabolism of HPV-positive tumors in a way that stops the growth of tumors. The purpose of this study is to understand how Fenofibrate can be used to treat HPV-positive cervical cancers and cervical dysplasia. Researchers will examine collected tissue samples and investigate various genes and proteins to see whether Fenofibrate has an effect on HPV-positive cervical cancers and cervical dysplasia.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06191133
Study type Interventional
Source Case Comprehensive Cancer Center
Contact Lindsay A Ferguson, MD
Phone 216-844-3954
Email lindsay.ferguson@uhhospitals.org
Status Not yet recruiting
Phase Phase 1
Start date August 1, 2024
Completion date May 31, 2025
View Details
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