Clinical Trials Logo

Clinical Trial Summary

TO Compare The Clinical And Radiographic Outcomes of DCI VS ACDF For The Treatment Of Single-Level Cervical Degenerative Disc Disease (DDD)


Clinical Trial Description

Anterior cervical discectomy and fusion (ACDF) is an effective and safe treatment for patients with radiculopathy and myelopathy. However, in the untreated levels adjacent to a fusion, increased motion and elevated intradiscal pressures have been reported. Some investigators have postulated that these changes may lead to an increased risk of adjacent segment degeneration (ASD). Limitations and problems with ACDF have led some investigators to explore the motion-preserving surgeries, such as cervical total disk replacement (TDR). Although TDR has been shown to reduce adjacent-level intra discal pressures and provide a more physiological overall cervical but also index- and adjacent-level range of motion (ROM) while maintaining sagittal alignment. Recent studies have also highlighted the potential limitations of TDR. Dynamic cervical implant (DCI) is a type of anterior decompression and cervical non-fusion implant that was initially conceived as a method to combine the potential advantages of fusion and TDR. The DCI is intended to provide controlled, limited flexion and extension-the primary motions in the sub axial cervical spine-that is greater than that seen with fusion, but less than that achieved with TDR . ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05522010
Study type Interventional
Source Assiut University
Contact Mahmoud Saleh El Attar, Master
Phone 01014919050
Email attar@med.aun.edu.eg
Status Not yet recruiting
Phase N/A
Start date August 25, 2022
Completion date August 1, 2024

See also
  Status Clinical Trial Phase
Not yet recruiting NCT06383962 - Post-Market Data Collection to Evaluate the Performance of the Synergy Disc®
Not yet recruiting NCT06413225 - Post-Market Data Collection Protocol to Evaluate the Performance of the Synergy Disc®
Active, not recruiting NCT04469231 - The Synergy Disc To Anterior Cervical Discectomy and Fusion N/A
Completed NCT02417272 - Total Disc Replacement Versus Anterior Cervical Decompression and Fusion N/A
Completed NCT02667067 - Investigation of the Simplify® Cervical Artificial Disc N/A
Withdrawn NCT01616719 - Evaluation of DTRAX Graft in Patients With Cervical Degenerative Disc Disease N/A
Terminated NCT00700739 - Study to Investigate the Performance of Cervical Arthroplasty for the Treatment of Cervical Degenerative Disc Disease Phase 4
Terminated NCT00637312 - Advent™ Cervical Disc Versus ACDF for Treatment of One Level Degenerative Disc Disease (IDE Study) N/A
Terminated NCT03062657 - An Investigation of the Metal Concentration in Patients Implanted With the PRESTIGE LP™ Cervical Disc at Two Contiguous Levels in the Cervical Spine N/A
Completed NCT01106417 - Safety and Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy and Fusion Phase 1/Phase 2
Completed NCT01097486 - Safety and Preliminary Efficacy Study of NeoFuse in Subjects Undergoing Multi-Level Anterior Cervical Discectomy Phase 2
Completed NCT00637156 - Study of the Safety and Effectiveness of the Artificial Cervical Disc - Low Profile Device at Two Adjacent Levels N/A
Completed NCT00437190 - Pivotal IDE Study of the BRYAN(R) Cervical Disc Prosthesis in the Treatment of DDD Versus ACDF N/A
Recruiting NCT05740176 - The Synergy Disc for the Treatment of 2 Level Cervical Degenerative Disc Disease Compared With Cervical Fusion Surgery N/A
Completed NCT00432159 - Comparison of DISCOVER™ Artificial Cervical Disc and ACDF for Treatment of Cervical DDD (IDE Study) N/A
Completed NCT00667459 - Study of Safety & Effectiveness of PRESTIGE® LP Cervical Disc vs. Anterior Cervical Fusion in Cervical DDD Phase 3
Recruiting NCT05880823 - Post Market Data Collection Protocol to Evaluate the Performance of the Synergy Disc
Recruiting NCT06383949 - Real World Data Collection on the Synergy Disc
Terminated NCT01291134 - PureGen: Radiographic Analysis of Fusion for ACDF
Terminated NCT00640029 - Evaluation of the Prosthetic Disc Replacement N/A