Cervical Cancer Clinical Trial
Official title:
A Randomized Controlled Trial Comparing Concomitant HPV-cytology Testing With Conventional Cytology Testing for the Detection of High Grade Cervical Intraepithelial Neoplasia in Primary Cervical Cancer Screening in Hong Kong
To compare the effects of conventional cytology testing with concommitant HPV-cytology
testing for the detection of high grade cervical lesions in primary cervical cancer
screening in Hong Kong
Hypotheses:
1. There is a significant difference in the number of CIN2+ cases detected between the
cytology testing group and the cytology-HPV co-testing group at baseline.
2. Significantly more CIN2+ cases will be detected at the second round of screening among
participants with normal cytology result in the control arm than those with normal
cytology and negative HPV results in the intervention arm.
n/a
Allocation: Randomized, Intervention Model: Parallel Assignment, Masking: Double Blind (Subject, Investigator), Primary Purpose: Prevention
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