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Cervical Cancer clinical trials

View clinical trials related to Cervical Cancer.

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NCT ID: NCT06419673 Active, not recruiting - Cervical Cancer Clinical Trials

Serplulimab Plus Chemoradiotherapy for Stage III-IVA Cervical Cancer

Start date: May 1, 2024
Phase: Phase 2
Study type: Interventional

This study is a prospective, multicenter, randomized, open controlled clinical trial aimed at evaluating the effectiveness and safety of serplulimab plus chemoradiotherapy in FIGO 2018 stage III or IVA cervical squamous cell carcinoma, adenocarcinoma, and adenosquamous cell carcinoma patients who have not received prior treatment.

NCT ID: NCT05939440 Active, not recruiting - Cervical Cancer Clinical Trials

Interventions to Decrease Financial Toxicity

P-COC
Start date: June 1, 2022
Phase: N/A
Study type: Interventional

Financial distress affects 30-70% of cancer patients and describes the burden that patients experience due to the costs of care (CoC). One reason may be because patients lack the appropriate information on CoC that would help them better plan for and manage their CoC. Therefore, the investigators plan to test a Proactive CoC intervention which includes a discussion with a trained educator on CoC information and a Cost Tracking tool to help patients deal with their CoC.

NCT ID: NCT05899647 Active, not recruiting - Cervical Cancer Clinical Trials

Point-of-Care Ultraviolet Microscopy for Cervical Cancer Screening

Start date: November 27, 2023
Phase: N/A
Study type: Interventional

This study aims to determine the image features of cervical cells, as measured via ultraviolet microscopy, that would constitute a positive screening and a negative screening result for cervical dysplasia, a precursor to cervical cancer, as measured against liquid-based Papanicolaou testing.

NCT ID: NCT05613283 Active, not recruiting - Cervical Cancer Clinical Trials

Primary Cervical Cancer Screening by Self-sampling HPV Test

PREVENT
Start date: November 19, 2022
Phase:
Study type: Observational

Cervical cancer seriously threatens women's health and HPV infection is the main cause of cervical cancer. Traditionally, Cervical cancer screening is based on cervical exfoliated cell samples collected by health care provider, which is labor consuming and the coverage and compliance are both relatively low in some areas. Non-invasive hrHPV self-sampling test appears to be more acceptable and may improve the HPV screening coverage. This study aims to evaluate the clinical performance of a newly developed urine/vaginal self-sampling hrHPV test in Cervical cancer screening.

NCT ID: NCT05580341 Active, not recruiting - Cervical Cancer Clinical Trials

Phase III Study Comparing the Immunogenicity of 9-valent HPV Recombinant Vaccine and Gardasil-9

Start date: September 1, 2022
Phase: Phase 3
Study type: Interventional

This study will evaluate the immunogenicity and safety of Zerun 9-valent HPV recombinant vaccine in healthy female 16-26 years of age by comparing with GARDASIL®9.

NCT ID: NCT05453006 Active, not recruiting - Cervical Cancer Clinical Trials

HPV Self-Sampling in Somali Women

Isbaar
Start date: February 20, 2023
Phase: N/A
Study type: Interventional

This study plans to assess the effect of implementing HPV self-sampling in primary care on uptake of cervical cancer screening in 30-65 year old Somali women who are due for cervical cancer screening.

NCT ID: NCT05311618 Active, not recruiting - Breast Cancer Clinical Trials

Study of NGM438 as Monotherapy and in Combination With Pembrolizumab in Advanced or Metastatic Solid Tumors

Start date: May 11, 2022
Phase: Phase 1
Study type: Interventional

Study of NGM438 as Monotherapy and in Combination with Pembrolizumab in Advanced or Metastatic Solid Tumors

NCT ID: NCT05179317 Active, not recruiting - Cervical Cancer Clinical Trials

Safety and Efficacy Study of First-line Treatment With QL1706 Plus Chemotherapy With or Without Bevacizumab in Women With Recurrent, or Metastatic Cervical Cancer

Start date: May 30, 2021
Phase: Phase 2
Study type: Interventional

This is a Phase 2, multicenter, open label, single arm study designed to evaluate the efficacy, safety, tolerability, pharmacokinetic (PK), and immunogenicity of QL1706 Plus Chemotherapy in Women With Recurrent, or Metastatic Cervical Cancer.

NCT ID: NCT05063916 Active, not recruiting - Cervical Cancer Clinical Trials

Phase II Study of AK104 (Cadonilimab) for Recurrent Small Cell Neuroendocrine Carcinomas of the Cervix

Start date: February 28, 2022
Phase: Phase 2
Study type: Interventional

This is a Phase 2, single center, open-label, single-arm study designed to evaluate the efficacy, safety, tolerability, and immunogenicity of AK104 monotherapy in adult subjects with previously treated recurrent or metastatic high grade neuroendocrine cervical cancer.

NCT ID: NCT05059015 Active, not recruiting - Cervical Cancer Clinical Trials

Human Papilloma Virus (HPV) Self-collection and Women Adherence

Start date: May 1, 2019
Phase: N/A
Study type: Interventional

Despite declining mortality in high-income countries, cervical cancer continues to be a public health problem in low and middle -income countries. HPV tests have shown a better sensibility and a higher capacity of reducing mortality than cytology based-screening. Greater participation has been demonstrated with the use of HPV self-testing when it is offered to women with a poor screening history; however, it is not clear whether getting tested necessarily translates into a greater adherence to the entire clinical protocol, including diagnosis and treatment of precancerous lesions. The aim of this study is to evaluate the effect of the self-testing techniques on the participation and adherence of women to cervical cancer screening.