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Cervical Cancer clinical trials

View clinical trials related to Cervical Cancer.

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NCT ID: NCT05899647 Active, not recruiting - Cervical Cancer Clinical Trials

Point-of-Care Ultraviolet Microscopy for Cervical Cancer Screening

Start date: November 27, 2023
Phase: N/A
Study type: Interventional

This study aims to determine the image features of cervical cells, as measured via ultraviolet microscopy, that would constitute a positive screening and a negative screening result for cervical dysplasia, a precursor to cervical cancer, as measured against liquid-based Papanicolaou testing.

NCT ID: NCT05613283 Active, not recruiting - Cervical Cancer Clinical Trials

Primary Cervical Cancer Screening by Self-sampling HPV Test

PREVENT
Start date: November 19, 2022
Phase:
Study type: Observational

Cervical cancer seriously threatens women's health and HPV infection is the main cause of cervical cancer. Traditionally, Cervical cancer screening is based on cervical exfoliated cell samples collected by health care provider, which is labor consuming and the coverage and compliance are both relatively low in some areas. Non-invasive hrHPV self-sampling test appears to be more acceptable and may improve the HPV screening coverage. This study aims to evaluate the clinical performance of a newly developed urine/vaginal self-sampling hrHPV test in Cervical cancer screening.

NCT ID: NCT05580341 Active, not recruiting - Cervical Cancer Clinical Trials

Phase III Study Comparing the Immunogenicity of 9-valent HPV Recombinant Vaccine and Gardasil-9

Start date: September 1, 2022
Phase: Phase 3
Study type: Interventional

This study will evaluate the immunogenicity and safety of Zerun 9-valent HPV recombinant vaccine in healthy female 16-26 years of age by comparing with GARDASIL®9.

NCT ID: NCT05311618 Active, not recruiting - Breast Cancer Clinical Trials

Study of NGM438 as Monotherapy and in Combination With Pembrolizumab in Advanced or Metastatic Solid Tumors

Start date: May 11, 2022
Phase: Phase 1
Study type: Interventional

Study of NGM438 as Monotherapy and in Combination with Pembrolizumab in Advanced or Metastatic Solid Tumors

NCT ID: NCT05179317 Active, not recruiting - Cervical Cancer Clinical Trials

Safety and Efficacy Study of First-line Treatment With QL1706 Plus Chemotherapy With or Without Bevacizumab in Women With Recurrent, or Metastatic Cervical Cancer

Start date: May 30, 2021
Phase: Phase 2
Study type: Interventional

This is a Phase 2, multicenter, open label, single arm study designed to evaluate the efficacy, safety, tolerability, pharmacokinetic (PK), and immunogenicity of QL1706 Plus Chemotherapy in Women With Recurrent, or Metastatic Cervical Cancer.

NCT ID: NCT05107739 Active, not recruiting - Cervical Cancer Clinical Trials

A Study of DeTIL-0255 in Adults With Advanced Malignancies

Start date: December 22, 2021
Phase: Phase 1
Study type: Interventional

This is a first-in-human Phase 1 multicenter, open-label oncology study designed to evaluate the safety and efficacy of NX-DeTIL-0255-201 in patients with advanced malignancies.

NCT ID: NCT05059015 Active, not recruiting - Cervical Cancer Clinical Trials

Human Papilloma Virus (HPV) Self-collection and Women Adherence

Start date: May 1, 2019
Phase: N/A
Study type: Interventional

Despite declining mortality in high-income countries, cervical cancer continues to be a public health problem in low and middle -income countries. HPV tests have shown a better sensibility and a higher capacity of reducing mortality than cytology based-screening. Greater participation has been demonstrated with the use of HPV self-testing when it is offered to women with a poor screening history; however, it is not clear whether getting tested necessarily translates into a greater adherence to the entire clinical protocol, including diagnosis and treatment of precancerous lesions. The aim of this study is to evaluate the effect of the self-testing techniques on the participation and adherence of women to cervical cancer screening.

NCT ID: NCT05056402 Active, not recruiting - Cervical Cancer Clinical Trials

An Immuno-bridging Study of a Nonavalent HPV Vaccine (E.Coli) in Healthy Population Aged 9-17 vs Aged 18-26 Years Old

Start date: September 19, 2021
Phase: Phase 3
Study type: Interventional

This is a open label clinical trial to evaluate the safety and immunogenicity of a Recombinant Human Papillomavirus Nonavalent (Types 6,11,16,18,31,33,45,52,58)Vaccine(E.Coli) manufactured by Xiamen Innovax Biotech CO., Ltd., in healthy population aged 9-17 years old in comparison with aged 18-26.

NCT ID: NCT05047913 Active, not recruiting - Cervical Cancer Clinical Trials

Comprehensive Evaluation of Tumor Oxygenation, Metabolism and Blood Supply of High Grade Glioma and Cervical Cancers Using Dynamic FAZA PET and Multiparametric MR

Start date: September 20, 2021
Phase: Early Phase 1
Study type: Interventional

Primary Objectives To investigate the relationship between dynamic MRI, brain tumor perfusion (DSC) and permeability (DCE), and dynamic 18F-FAZA PET uptake. Secondary Objectives To investigate the relationship between tumors with greater hypoxia defined by qBOLD and 18F-FAZA PET and pathological features including proportionate necrosis, Ki-67 and IDH mutation status To investigate the correlation between the hypoxic tumor region delineated using 18F-FAZA PET and qBOLD

NCT ID: NCT05035173 Active, not recruiting - Breast Cancer Clinical Trials

The LYSA (Linking You to Support and Advice) Trial

LYSA
Start date: March 13, 2021
Phase: N/A
Study type: Interventional

This study's aim is to evaluate the feasibility of introducing a women's malignancy survivorship clinic incorporating symptom management through ePRO collection (complex intervention) into routine follow up care in patients with early-stage Hormone Receptor(HR)-positive breast and gynaecologic cancer post primary curative therapy.