Treatment With AX200 for Acute Ischemic Stroke

Status Completed

Clinical Trial Summary

The AXIS study is a randomized, double-blind, placebo-controlled, dose-escalating phase IIa trial to investigate treatment with AX200 (granulocyte-colony stimulating factor; G-CSF) for acute ischemic stroke. The primary objective of the present phase IIa study is to assess the safety and tolerability of AX200 compared to placebo in subjects suffering from acute stroke. The secondary objective is to assess the effect of AX200 on subject outcome in comparison to placebo.

Clinical Trial Description

n/a

Study Design

Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Single Group Assignment, Masking: Double-Blind, Primary Purpose: Treatment

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00132470
Study type	Interventional
Source	Axaron Bioscience AG
Contact
Status	Completed
Phase	Phase 2
Start date	December 2004
Completion date	March 2007

View Details

See also
Status	Clinical Trial	Phase
Completed	`NCT03281590` - Stroke and Cerebrovascular Diseases Registry
Recruiting	`NCT03685578` - CERENOVUS Neurothrombectomy Devices Registry
Recruiting	`NCT05591183` - CERENOVUS Neurothrombectomy Devices Registry
Completed	`NCT04465019` - Exoskeleton Rehabilitation on TBI
Completed	`NCT02827825` - Patients Undergoing Strokes Admitted in Intensive Care Requiring Neurosurgical ICU Crossing: Patient Profile and Prognosis
Recruiting	`NCT02077582` - Longitudinal MRI Examinations of Patients With Brain Ischemia and Blood Brain Barrier Permeability	N/A
Terminated	`NCT01705353` - The Role of HMGB-1 in Chronic Stroke	N/A
Completed	`NCT01732679` - Sunnaas International Network´s Stroke Study	N/A
Completed	`NCT01182818` - Fabry and Stroke Epidemiological Protocol (FASEP): Risk Factors In Ischemic Stroke Patients With Fabry Disease	N/A
Completed	`NCT00311025` - Stroke: Reduction of Physical Performance Post Stroke. Inactivity or Secondary Complications?	Phase 1/Phase 2
Withdrawn	`NCT03804125` - A Study of Adverse Events and Suspected Adverse Drug Reactions in Patients Under Apixaban for Prevention of Stroke and Systemic Embolism With Non-Valvular Atrial Fibrillation and Venous Thromboembolic Events in Patients Who Have Undergone Elective Hip or Knee Replacement Surgery
Completed	`NCT05435404` - Qualitative Study Patient & Physician Experiences Botox COVID-19
Completed	`NCT03898960` - Post Marketing Study to Evaluate the NIMBUS Device
Not yet recruiting	`NCT06087094` - A Trial of HRS-7450 in Chinese Healthy Volunteers	Phase 1
Completed	`NCT02207023` - Healthy Lifestyles After Stroke - Stroke Coach	N/A
Active, not recruiting	`NCT02017574` - Motor Learning in Stroke	Phase 0
Completed	`NCT02002390` - Efficacy and Safety of FTY720 for Acute Stroke	Phase 2
Completed	`NCT01864382` - "Core Stability" Exercises to Improve Sitting Balance in Stroke Patients	N/A
Recruiting	`NCT04447599` - Conjunctival and Retinal Vascularization and Small Vessel Disease	N/A
Recruiting	`NCT04157179` - Cerebral Oxygen Metabolism in Children	N/A