Rhythm and Multisensoriality's Effects on the Motor Development in Children With Cerebral Palsy

Cerebral Palsy Clinical Trial

— APP-PaC  

Official title:

Rhythm and the Multisensoriality's Effects on the Motor Development in Children With Cerebral Palsy

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT03440749
• Other study ID #: RC31/17/0158
• Secondary ID: 2017-A01969-44
• Status: Recruiting
• Phase: N/A
• Start date: February 15, 2018
• Est. completion date: August 2020

Study information

• Verified date: October 2019
• Source: University Hospital, Toulouse
• Contact: Philippe Marque, MD
• Phone: 5-61-32-28-01
• Email: marque.ph[@]chu-toulouse.fr
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Cerebral palsy (CP) affects the motor function but also the cognitive function of the child. Physical activity brings motor and cognitive benefits and appears as an important aspect of the therapy that is offered to them.

The child is seating in front of a computer, seating comfortably on a chair during 1 hour. The experimental task consists in learning a sequence of taps on "Serial reaction time task" type buzzers (SRTT) in which the child must press a buzzer corresponding to one of the 4 squares that on the screen. The sequence corresponds to 10 steps in a particular order.

Description:

Cerebral palsy (CP) affects the motor function but also the cognitive function of the child. Physical activity brings motor and cognitive benefits and appears as an important aspect of the therapy that is offered to them. In particular, the learning of movements in the presence of multisensory rhythmic information seems to have beneficial effects at the cognitive and motor level. The present study aims to test the respective effects of rhythm and multisensoriality on motor learning in children with cerebral palsy.

The motor learning task is known as the "Serial Reaction Time Task" (SRTT). It consists in repeating a sequence of movements of the upper limbs using visual-spatial information alone (V). It will test the addition of synchronous auditory stimulation to visual information or rhythmic auditory stimulation(VAR), to contrast with a control condition with non-rhythmic auditory stimulation (VANR). The performance of the children will be measured by the reaction time (RT), its stability and the number of errors made throughout the motor learning.

The child is placed in front of a screen on which 4 luminous stimuli are presented on a horizontal plane. Four buzzers are placed in front of him, each buzzer corresponds to the position of a stimulus. The stimuli light up in a predetermined sequence (10 positions) and the child must press the buzzer corresponding to the position of the stimulus that comes on. Four blocks of 5 sequences are repeated to test the general learning (B1 to B4) and then a block of random stimuli is presented to test the specific learning of the sequence (B5).

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 60
• Est. completion date: August 2020
• Est. primary completion date: August 2020
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 6 Years to 14 Years

Eligibility

Inclusion Criteria:

For all children:

• Age between 6 and 14 years

• Obtaining the informed consent of the person possessing parental authority for all children

For children with Cerebral Palsy:

• Diagnosis of spastic cerebral palsy of levels GMFCS I to IV

• Ability to press buzzers with the palm of the hand, Manual Ability Classification System (MASC) I to IV

• Ability to understand instructions ("tap a buzzer along with a picture or sound") (investigator's appreciation)

For control children: no pathology diagnosed

Exclusion Criteria:

For all children:

• Children with a characteristic psychiatric pathology.

• Disorders of the understanding

• Hearing deficiency

• Uncorrected visual impairment

Related Conditions & MeSH terms

• Cerebral Palsy

Intervention

Other:
• luminous stimuli
The child is placed in front of a screen on which 4 luminous stimuli are presented on a horizontal plane. Four buzzers are placed in front of him, each buzzer corresponds to the position of a stimulus. Child had to push the buzzer corresponding to the place of the luminous stimuli.

Locations

Country	Name	City	State
France	University Hospital Toulouse	Toulouse

Sponsors (2)

Lead Sponsor	Collaborator
University Hospital, Toulouse	Institut National de la Santé Et de la Recherche Médicale, France

Country where clinical trial is conducted

France, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Other	Multisensory integration degree	Multisensory integration degree evaluated in pre-test	1 hour
Other	Degree of synchronization	Degree of synchronization evaluated in pre-test	1 hour
Primary	Time reaction (TR)	- The TR is the Reaction Time between the appearance of the stimulus and the response. It represents the speed with which the child pressed the key in response to the lighting of the square.	1 hour
Secondary	Number of errors	The number of errors corresponds to pressing a key that does not correspond to the position of the lit square.	1 hour