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Safety and Efficacy of Multiple EPO Injections in Children With Cerebral Palsy

Cerebral Palsy Clinical Trial

Official title:
Safety and Efficacy of Repetitive Erythropoietin Treatment for Cerebral Palsy

Clinical Trial Summary

This study is a retrospective review on the safety and efficacy of repetitive erythropoietin injection in children with cerebral palsy

Clinical Trial Description

Cerebral palsy is mostly caused by hypoxic-ischemic encephalopathy from preterm birth, involving inflammatory and apoptotic cellular response. Erythropoietin (EPO) has shown neuroprotective effects via activation of anti-inflammatory, angiogenic, and anti-apoptotic pathways. The safety and feasibility of EPO in children were proven in previous clinical trials. In addition, the efficacy of EPO is actively being investigated and some reports have shown potential benefits in cerebral palsy. To confirm the safety and efficacy of multiple injections with expected effect, retrospective review on medical records was performed. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03303573
Study type Observational
Source Bundang CHA Hospital
Contact
Status Completed
Phase N/A
Start date January 1, 2013
Completion date August 2017
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