Clinical Trials Logo

Clinical Trial Summary

To evaluate the safety and efficacy of neural stem cells (NSCs) therapy for cerebral palsy.

Clinical Trial Description

Cerebral palsy is the most severe lifelong disability disease in childhood. In China, an epidemiological investigation of cerebral palsy in 2004 has reported that 2.74‰ (about 6.50-9.75 million) of children suffered from cerebral palsy. The costs of medical expenses, living allowance and nursing care can go up to RMB 20000-50000 yuan per year for each child with cerebral palsy and thus China will expend RMB 120-300 billion yuan per year for children with cerebral palsy. With full liberalization of two-child policy, there is an increasing number of second babies born to women who are 35 years or older. Thus, the incidence of cerebral palsy tends to increase. There is currently no cure for cerebral palsy, resulting in a heavy burden for families and on society. Recent clinical trials performed in countries outside China have demonstrated that stem cell therapy is likely the most effective method to treat cerebral palsy. Fifteen trials regarding stem cell therapy for cerebral palsy have been registered with In China, there have been no standardized registered trials regarding stem cell therapy for cerebral palsy, which greatly restricts its clinical application. In October 2016, the National Health and Family Planning Commission and the Food and Drug Administration of China jointly announced the premier stem cell clinical research institutions, making performing standardized trials regarding stem cell therapy for cerebral palsy in China possible. ;

Study Design

Related Conditions & MeSH terms

NCT number NCT03005249
Study type Interventional
Source The First Affiliated Hospital of Dalian Medical University
Contact Jing Liu, Ph.D
Phone 86041184394568
Email [email protected]
Status Recruiting
Phase N/A
Start date December 2016
Completion date December 2019

See also
  Status Clinical Trial Phase
Active, not recruiting NCT03264339 - The Small Step Program - Early Intervention for Children With High Risk of Developing Cerebral Palsy N/A
Completed NCT03902886 - Independent Walking Onset of Children With Cerebral Palsy
Not yet recruiting NCT04081675 - Compliance in Children With Cerebral Palsy Supplied With AFOs
Completed NCT04012125 - The Effect of Flexible Thoracolumbar Brace on Scoliosis in Cerebral Palsy N/A
Recruiting NCT04489498 - Comparison of Somatometric Characteristics Between Cerebral Palsy and Normal Children, Cross-sectional, Multi Center Study
Completed NCT03677193 - Biofeedback-enhanced Interactive Computer-play for Youth With Cerebral Palsy N/A
Recruiting NCT04093180 - Intensive Neurorehabilitation for Cerebral Palsy N/A
Completed NCT02909127 - The Pediatric Eating Assessment Tool
Not yet recruiting NCT04899284 - Impact of Early Intensive Stimulation on Bimanual Function in Infants at High Risk of Unilateral CP (BB-BIM) N/A
Not yet recruiting NCT04096430 - Evaluation of Effectiveness of Child-oriented Goal-setting in Paediatric Rehabilitation (the ENGAGE Approach) N/A
Not yet recruiting NCT03183427 - Corpus Callosum Size in Patients With Pineal Cyst N/A
Active, not recruiting NCT03078621 - Bone Marrow-Derived Stem Cell Transplantation for the Treatment of Cerebral Palsy Phase 1/Phase 2
Completed NCT02849938 - Evaluating the Value of Telehealth for Care of Children With Medical Complexity N/A
Completed NCT02897024 - A Comparison: High Intense Periodic vs. Every Week Therapy in Children With Cerebral Palsy (ACHIEVE) N/A
Recruiting NCT02596412 - Augmented Reality to Reduce Pain During Botulinum Toxin Injections in Cerebral-palsied Children N/A
Recruiting NCT02546999 - Does Botulinum Toxin A Make Walking Easier in Children With Cerebral Palsy? Phase 4
Completed NCT02699554 - Quantifying Patient-Specific Changes in Neuromuscular Control in Cerebral Palsy
Not yet recruiting NCT02545179 - Web-based Daily Care Training of Children With Cerebral Palsy N/A
Active, not recruiting NCT02918890 - Intensive Unimanual (CIMT) and Bimanual Training (HABIT) in Children With Hemiplegia N/A
Completed NCT01650415 - Erythropoietin Therapy for Children With Cerebral Palsy Phase 2