Cerebral Palsy Clinical Trial
Official title:
Effectiveness of Modified Constraint-induced Movement Therapy and Self-regulation Learning for Children With Hemiplegic Cerebral Palsy
This study examines the effect of combining modified constraint-induced movement therapy (mCIMT) and self-regulation (SR) in promoting upper limb function of children with hemiplegic cerebral palsy (CP) studying in a school-based setting.
Children diagnosed with hemiplegic CP are involved. A within-subject design is used with
children acting as their own controls. The study is scheduled at three-week intervals. All
children undergo conventional occupational therapy (OT) and modified constraint-induced
movement therapy plus self-regulation (mCIMT + SR) program in a random order.
Both programs last for three weeks. Each program is followed by a three-week no-treatment
period to measure the carry-over effect. The OT program consists of training on unimanual
and bimanual tasks for 1 to 2 hours a week with daily home exercise. The mCIMT + SR program
involves restraint of the unaffected upper limb of children using a cotton sling for 6 hours
per day for 15 days. A one-hour structured task practice with the use of SR is provided
during each 6-hour restraint.
The Bruininks-Oseretsky Test of Motor Proficiency, the Jebsen-Taylor Test of Hand Function,
the Caregiver Functional Use Survey, a hand dynamometer, pinch gauge, and modified Ashworth
scale are used for evaluation. All children are assessed for five times at 3-week interval:
once before and twice after the conventional OT; and twice after the mCIMT + SR at 1 week
and at 3 weeks.
Before and after the three-week intervention, the children participate in event-related
potentials (ERP) sessions with a choice reaction task. Event-related potentials (ERP)
technique is used to capture the changes in neural mechanism after intervention.
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Allocation: Non-Randomized, Endpoint Classification: Efficacy Study, Intervention Model: Parallel Assignment, Masking: Single Blind (Outcomes Assessor), Primary Purpose: Treatment
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