Allogeneic UCB Therapy With EPO in Children With CP

Status Completed

Clinical Trial Summary

This randomized controlled study aims to evaluate the efficacy and safety of allogeneic umbilical cord blood therapy combined with erythropoietin for children with cerebral palsy.

Clinical Trial Description

Cerebral palsy (CP) is a group of neurodevelopmental conditions with abnormal movement and posture resulted from a non-progressive cerebral disturbance. It is the most common cause of motor disability in childhood. Most therapies are palliative rather than restorative. Umbilical cord blood (UCB) and erythropoetin (EPO) may be used as restorative approach for children with CP.

Many experimental animal studies have revealed that UCB is beneficial to improve and repair neurological injuries. EPO is also known to have neuroprotective effects.

Based on animal studies and some clinical trials, UCB is suggested as a potential therapy for children with CP. EPO is combined to add synergistic effects to UCB therapy. ;

Study Design

Related Conditions & MeSH terms

Cerebral Palsy

Clinical Trial Details

NCT number	NCT01991145
Study type	Interventional
Source	Bundang CHA Hospital
Contact
Status	Completed
Phase	N/A
Start date	November 26, 2013
Completion date	June 24, 2017

View Details

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