Cerebral Palsy Clinical Trial
Official title:
Evaluation of MR Imaging to Predict Neurodevelopmental Impairment in Preterm Infants
Preterm infants face an uncertain future because premature birth often leads to problems
with brain development and can cause cerebral palsy.
A trial needs to be done to see if Magnetic Resonance Imaging (MRI) helps families and
professionals by predicting long term problems more accurately, allowing better targeting of
care to children with problems and reassuring the parents of normal babies.
This programme will provide the evidence-base for the National Health System (NHS) policy on
the use of magnetic resonance imaging of the brain for preterm infants.
The trial will determine very accurately how well MRI predicts long-term problems, and it
will assess whether it makes parents more or less anxious about their babies, and whether
they seek more or less help in the first couple of years after birth,and see if the total
cost to the NHS is increased by using MRI. It will also check up if there is a better way to
do ultrasound examinations, and do a survey to see how much MRI is used in the United
Kingdon (UK) and whether hospitals think they could provide it.
The core of the project is a study of preterm babies who will be referred to a specialist
centre to have both ultrasound and MRI scans. Half the parents will be told the results of
the MRI and half the parents the ultrasound. The programme will then ask them to fill in
questionnaires or be interviewed about their stress levels and the amount of support they
seek for their children until they are two years old, when the babies will be examined to
see if MRI predicted their outcome accurately.
;
Observational Model: Cohort, Time Perspective: Prospective
| Status | Clinical Trial | Phase | |
|---|---|---|---|
| Recruiting |
NCT05317234 -
Genetic Predisposition in Cerebral Palsy
|
N/A | |
| Recruiting |
NCT05576948 -
Natural History of Cerebral Palsy Prospective Study
|
||
| Completed |
NCT04119063 -
Evaluating Wearable Robotic Assistance on Gait
|
Early Phase 1 | |
| Completed |
NCT03264339 -
The Small Step Program - Early Intervention for Children With High Risk of Developing Cerebral Palsy
|
N/A | |
| Completed |
NCT05551364 -
Usability and Effectiveness of the ATLAS2030 Exoskeleton in Children With Cerebral Palsy
|
N/A | |
| Completed |
NCT03902886 -
Independent Walking Onset of Children With Cerebral Palsy
|
||
| Recruiting |
NCT05571033 -
Operant Conditioning of the Soleus Stretch Reflex in Adults With Cerebral Palsy
|
N/A | |
| Not yet recruiting |
NCT04081675 -
Compliance in Children With Cerebral Palsy Supplied With AFOs
|
||
| Completed |
NCT02167022 -
Intense Physiotherapies to Improve Function in Young Children With Cerebral Palsy
|
N/A | |
| Completed |
NCT04012125 -
The Effect of Flexible Thoracolumbar Brace on Scoliosis in Cerebral Palsy
|
N/A | |
| Enrolling by invitation |
NCT05619211 -
Piloting Movement-to-Music With Arm-based Sprint-Intensity Interval Training Among Children With Physical Disabilities
|
Phase 1 | |
| Completed |
NCT04489498 -
Comparison of Somatometric Characteristics Between Cerebral Palsy and Normal Children, Cross-sectional, Multi Center Study
|
||
| Completed |
NCT03677193 -
Biofeedback-enhanced Interactive Computer-play for Youth With Cerebral Palsy
|
N/A | |
| Recruiting |
NCT06450158 -
Robot-assisted Training in Children With CP
|
N/A | |
| Completed |
NCT04093180 -
Intensive Neurorehabilitation for Cerebral Palsy
|
N/A | |
| Completed |
NCT02909127 -
The Pediatric Eating Assessment Tool
|
||
| Not yet recruiting |
NCT06377982 -
Human Umbilical Cord Blood Infusion in Patients With Cerebral Palsy
|
Phase 1 | |
| Not yet recruiting |
NCT06007885 -
Examining Capacity Building of Youth With Physical Disabilities to Pursue Participation Following the PREP Intervention.
|
N/A | |
| Not yet recruiting |
NCT03183427 -
Corpus Callosum Size in Patients With Pineal Cyst
|
N/A | |
| Active, not recruiting |
NCT03078621 -
Bone Marrow-Derived Stem Cell Transplantation for the Treatment of Cerebral Palsy
|
Phase 1/Phase 2 |