Cerebral Palsy Clinical Trial
Official title:
Wavelet Analysis of Surface EMG in Cerebral Palsy
Several methods exist to evaluate motor function in the child with cerebral palsy and are
used to assess the outcome of a clinical intervention. However, these scales are not
directed towards measuring the changes in muscle activity patterns that can result from the
intervention. For example, there are classification scales aimed at measuring motor function
and functional abilities, and indices of gait function. These scores, while providing a way
to quantify function and mechanics, do not directly measure muscle activation
characteristics. Therefore, these tests may be insensitive to how the intervention has
directly affected muscle function, which is usually the focus of the intervention (i.e.
botulinum toxin, functional electrical stimulation, dorsal rhizotomy). Muscle biopsies and
motor evoked potentials can provide information about the muscle activation characteristics,
however, they are invasive and there are concerns about using these techniques on the
pediatric population and/or the practicality of clinical implementation, especially since
they do not provide insight into how the muscle behaves during a functional task. One method
that can be used to provide insight into muscle activity in a non-invasive and clinically
meaningful manner is the use of surface electromyography (sEMG). Surface EMG is typically a
routine part of clinical assessment and the evaluation of motor impairment in CP. However,
the analysis of the data has been limited in most cases to examination of signal amplitude
or differences in muscle onset and offset timing.
The long-term goal of this research is to develop an analysis method for sEMG that can be
used during functional tasks for treatment planning, diagnostic, assessment purposes in CP.
This is to be accomplished through the use of the continuous wavelet transform (CWT). By
developing an assessment method based on muscle activity, it is believed that a clinically
viable measurement tool can be devised that will provide a level of insight into the effects
of an intervention on muscle pathophysiology that is not currently available. The first step
in progressing towards this long-term goal is to determine the variability and range of
expected time-frequency patterns that can be expressed in a given population (i.e., cerebral
palsy) during the execution of a meaningful task (gait), and relate the time-frequency
information back to more standard assessments
n/a
Observational Model: Case Control, Time Perspective: Prospective
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