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Cerebral Palsy clinical trials

View clinical trials related to Cerebral Palsy.

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NCT ID: NCT05463159 Recruiting - Cerebral Palsy Clinical Trials

Effects of Transcutaneous Electrical Nerve Stimulation on Spasticity in Children With Cerebral Palsy

Start date: January 13, 2022
Phase: N/A
Study type: Interventional

Cerebral Palsy (CP) is a group of mental disorder that disrupts the person's ability of moving, maintaining their balance and posture. Cerebral palsy is a motor disorganization in Childhood. Cerebral palsy can occur before birth, during birth, within a month after birth, or during 1st year of life when brain is under development. Symptoms vary from person to person in case of severe CP child must needs the equipment used to enhance their mobility and to train muscles. Transcutaneous electrical nerve stimulation (TENS) is method of relieving pain by using mild electric current. Purpose of this study will be to determine effects of TENS on spasticity and gross motor function in children with cerebral palsy. TENS is a small machine operated with battery containing attached sticky pads known as electrodes placed on stiffed and painful area of muscles. Classified by Ashworth Scale and Modified Tardieu Scale. Subjects will be randomly divided into four groups 1) Group A= TENS on spastic muscle/agonist, 2) Group B= TENS on antagonist, 3) GroupC= TENS on both agonist and antagonist muscle, Group D= conventional physiotherapy total treatment period is about 3 to 6 weeks. This study will help to discuss how much extent TENS will effect spasticity in children with cerebral palsy. Data will be analyzed through SPSS 22

NCT ID: NCT05460936 Recruiting - Cerebral Palsy Clinical Trials

Lower Extremity Functional Training (LIFT) on Gross Motor Function and Gait in Children With Spastic CP

LIFT
Start date: May 18, 2022
Phase: N/A
Study type: Interventional

Cerebral Palsy is a developmental disorder caused by damage to the brain before, during or after birth. Spastic Cerebral Palsy is one of the most common types of cerebral Palsy. It affects about 80% of cerebral palsy. Spastic CP is characterized by increased muscle tone, jerky movements, joint stiffness, and muscle tightness. Spastic Cerebral primarily affects strength, coordination, and balance resulting in gait difficulties and affecting gross motor functioning. These abnormalities affect the very basic activities of daily life (ADLs). Even if the child is able to walk the motor skills are usually disturbed which are very important to improve and maintain gross motor functioning. Physical therapy plays a vital role in overcoming these issues.

NCT ID: NCT05460923 Recruiting - Cerebral Palsy Clinical Trials

Pelvic Neuromuscular Facilitation and Swiss Ball Exercises on Trunk Control in Children With Diaplegic CP

Start date: May 25, 2022
Phase: N/A
Study type: Interventional

Cerebral palsy is an umbrella term that covers a group of non-progressive motor impairment syndromes that are associated with abnormalities in the brain particularly during the early stages of its development. CP usually involves a number of musculoskeletal and neurological problems they include spasticity, contractures, dystonia, abnormal growth, poor trunk control, and poor balance. Poor trunk control leads to a disturbance in activities of daily living along with postural issues. PNF techniques and Swiss ball exercises target the trunk muscles by stimulating the proprioceptors and by allowing maximum resistance to them respectively. The aim of the study is to do a comparison of Pelvic neuromuscular facilitation techniques and Swiss ball exercises in improving trunk control in children with diplegic cerebral palsy.

NCT ID: NCT05455970 Completed - Cerebral Palsy Clinical Trials

Effect of Rhythmic Auditory Stimulation on Balance in Children With Cerebral Palsy.

Start date: September 20, 2018
Phase: N/A
Study type: Interventional

To evaluate the effect of Rhythmic Auditory Stimulation (RAS) on balance in children with cerebral palsy.

NCT ID: NCT05447299 Enrolling by invitation - Cerebral Palsy Clinical Trials

Neuromusculoskeletal Modeling of Muscle Spasticity

Start date: January 15, 2019
Phase:
Study type: Observational

Cerebral palsy (CP) is a movement and posture disorder caused by an injury to the developing brain, with a prevalence in Sweden of about 2/1000 live births. Children with CP have walking difficulties, and decreased muscle mass and muscle function as compared to typically developing (TD) children. The extent of disability in CP depends on the severity and timing of the primary cerebral lesion and can be classified with the gross motor function classification system (GMFCS E&R) that ranges from walking without limitations (I) to being transported in a wheelchair (V). Muscle function commonly deteriorates with age and contracture development is often clinically evident as early as at 4 years of age. In addition to being thinner and weaker, skeletal muscle in children with CP develop poor quality, i.e., increasingly higher amounts of fat and connective tissue at the expense of functional, contractile proteins. How long-term standard treatments for children with spastic CP including, training and orthotics use, with botulinum toxin (BoNT-A) treatment as an adjunct, affects muscle on functional, structural, and microscopic level in CP has not yet been published. Therefore, we will investigate the muscle function as well as functional mobility, structure, and spasticity. We will conduct functional mobility tests. Muscle strength will be measured with a rig-fixed dynamometer, and muscle structure will be measured with magnetic resonance imaging. The spasticity will be instrumentally assessed by the NeuroflexorTM, a machine measuring resistance in a muscle when a pedal is passively moving the participants foot at two different speeds. We will follow participants, for 1 year, with 4 measurements during this period. In order to better treat these children, we need to better understand the complex, interrelated interactions of musculoskeletal properties and function in children with CP. Our hypothesis is that muscle structure and function is affected by standard clinical treatments sessions including routine botulinum toxin treatment. Analyzing the effect of standard care may help planning of more effective clinical treatments in the future.

NCT ID: NCT05444387 Enrolling by invitation - Cerebral Palsy Clinical Trials

The Effect of Upper Limb Loading During Partial Body Weight Support Treadmill Training in Children With Cerebral Palsy

Start date: July 1, 2022
Phase: N/A
Study type: Interventional

Objectives: To look for the effect of upper limb loading with external weights during partial body weight support treadmill training on gait speed, gait endurance and trunk control. Hypothesis: Investigator's hypothesis is that loading the upper limb with 1 lb. external weights during partial body weight support treadmill training is more effective than partial body weight support treadmill training without loading of the upper limbs in improving gait speed, gait endurance and trunk control.

NCT ID: NCT05436847 Completed - Cerebral Palsy Clinical Trials

Effects of Proprioceptive Training With Routine PT on Gross Motor Function in Spastic Quadriplegic CP

Start date: December 1, 2021
Phase: N/A
Study type: Interventional

The proprioceptive training with a therapy regime enhances the body's somatosensory input that in result changes the body to be more functional in different types of interactions. This study is dedicated to finding out how much proprioception training is helpful in gross motor function level improvement and enhances functional activities of CP children

NCT ID: NCT05429281 Completed - Cerebral Palsy Clinical Trials

The Role of Pilates, Plyometrics, and Their Combination for Children With Unilateral Cerebral Palsy

Start date: February 7, 2021
Phase: N/A
Study type: Interventional

This study was conducted to compare the effect of Pilates-based core strengthening (PsCS) and plyometric-based muscle loading (PlyoML) and their combination on postural control, balance, and mobility in children with unilateral cerebral palsy (ULCP). Eighty-one children with ULCP were randomly allocated to the PsCS (n = 27), PlyoML (n = 27), or combined intervention (n = 27) group. Participants in the three groups were assessed for postural control, balance, and mobility on the pre and post-treatment occasions.

NCT ID: NCT05428865 Completed - Clinical trials for Diplegic Cerebral Palsy

Correlation Between Body Mass Index, Selective Motor Control and Functional Ability in Children With CP

Start date: January 24, 2022
Phase:
Study type: Observational

PURPOSE: To investigate the correlations between body mass index, spasticity, functional ability and isolated motor control in children with spastic diplegia. BACKGROUND: Cerebral palsy is primarily a disorder of movement and posture HYPOTHESES: There is no correlation between body mass index, spasticity, functional ability and isolated motor control in children with spastic diplegia. RESEARCH QUESTION: Is there a correlation between body mass index, spasticity, functional ability and isolated motor control in children with spastic diplegia?

NCT ID: NCT05423171 Recruiting - Cerebral Palsy Clinical Trials

Intensive Bimanual Intervention in Cerebral Palsy Children

Start date: June 30, 2021
Phase: N/A
Study type: Interventional

Motor disorders related to cerebral palsy are often accompanied by sensory, cognitive, perceptive, communication and behavioural impairments. It has already been shown that intensive bimanual intervention can improve arm movement, but its impact on the spontaneous use of the most affected arm in everyday life remains to be established. This project aims to understand the impacts of an intensive bimanual therapy on uni- and bi-manual motor functions as well as the spontaneous use of the most affected arm. Predictive value of neuroimaging variables will also be assessed.