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Cerebral Ischemia clinical trials

View clinical trials related to Cerebral Ischemia.

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NCT ID: NCT05053932 Recruiting - Sickle Cell Disease Clinical Trials

Long-term Comparative Cerebrovascular Outcome After Transplantation vs Standard Care in Sickle Cell Anemia

DREPAGREFFE2
Start date: October 7, 2022
Phase:
Study type: Observational

The purpose of the present observational study is to remotely reevaluate the cohort of 67 sickle cell patients with transcranial Doppler-detected cerebral vasculopathy included in the national "Sickle Cell Transplant" protocol and whose 1- and 3-year results were published in JAMA (Journal of the American Medical Association) in 2019 and in BHJ in 2020.

NCT ID: NCT04998357 Recruiting - Cerebral Ischemia Clinical Trials

Autologous Mitochondrial Transplant for Cerebral Ischemia

Start date: April 29, 2021
Phase: N/A
Study type: Interventional

The investigators propose to infuse healthy autologous mitochondria into cerebral vessels supplying brain tissue experiencing ischemia in patients who undergo standard-of- care endovascular reperfusion therapy.

NCT ID: NCT04583163 Recruiting - Stroke Clinical Trials

Variability in Transcranial Doppler Technique in Neuro-Critical Care Patients

Start date: September 22, 2020
Phase:
Study type: Observational

This study aims to determine the inter- and intra-variability of Transcranial Doppler (TCD) ultrasound in neuro-critical care patients who are planned for consecutive daily TCD evaluations.

NCT ID: NCT04522856 Recruiting - Cerebral Ischemia Clinical Trials

Anaesthesiological Routine Care for Thrombectomy in Cerebral Ischaemia

Start date: August 1, 2021
Phase:
Study type: Observational

Endovascular thrombectomy is the standard of care for acute ischaemic stroke due to large-vessel occlusion. Current guidelines for periprocedural anaesthesiological care give gross recommendations on management of stroke patients during recanalization, but lack detailed information. To determine how anaesthesiologists support endovascular thrombectomy with regard to anaesthetic technique, choice of substances, haemodynamic management, and ventilation. With a multivariate analysis, the investigators will look for the factors of anesthetic management that are independently correlated with a good or bad outcome.

NCT ID: NCT04167527 Recruiting - Cerebral Ischemia Clinical Trials

Endovascular Therapy for Low NIHSS Ischemic Strokes

ENDOLOW
Start date: September 5, 2020
Phase: Phase 2/Phase 3
Study type: Interventional

This study will test the hypothesis that patients presenting within 8 hours of onset with cerebral ischemia in the setting of proximal large vessel occlusions (LVO) and low baseline NIHSS scores (0-5) will have better 90-day clinical outcomes (mRS distribution) with immediate mechanical thrombectomy (iMT) compared to initial medical management (iMM).

NCT ID: NCT03607565 Recruiting - Cerebral Ischemia Clinical Trials

A New Parameter Derived From DSA to Evaluate Cerebral Perfusion

Start date: July 15, 2018
Phase:
Study type: Observational

This observational study focus on a new parameter of cerebral perfusion derived form digital substraction angiography.

NCT ID: NCT03318432 Recruiting - Stroke Clinical Trials

Stroke Recovery Initiative - Registry for Stroke Research Studies

Start date: February 9, 2013
Phase:
Study type: Observational [Patient Registry]

The Stroke Recovery Initiative is a nation-wide participant recruitment registry that connects people who have had a stroke with researchers who are working to develop new approaches to improve recovery after stroke.

NCT ID: NCT02846259 Recruiting - Clinical trials for Intracranial Aneurysm

The Clinical Benefit and Risk of Oral Aspirin for Unruptured Intracranial Aneurysm Combined With Cerebral Ischemia

CBROAUNACCI
Start date: January 2016
Phase: N/A
Study type: Observational [Patient Registry]

The first purpose of this study is to find out the clinical benefit and risk of oral aspirin for unruptured intracranial aneurysm (small than 7mm) combined with cerebral ischemia in patients in the real world. The second purpose of this study is to get the prediction model of aneurysm's rupture in patients who has unruptured intracranial aneurysm (small than 7mm) combined with cerebral ischemia , and find out who is suitable for oral aspirin.

NCT ID: NCT02795052 Recruiting - Stroke Clinical Trials

Neurologic Stem Cell Treatment Study

NEST
Start date: June 2016
Phase: N/A
Study type: Interventional

This is a human clinical study involving the isolation of autologous bone marrow derived stem cells (BMSC) and transfer to the vascular system and inferior 1/3 of the nasal passages in order to determine if such a treatment will provide improvement in neurologic function for patients with certain neurologic conditions. http://mdstemcells.com/nest/